DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7737 and il4i1

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	XP_009289997.1	Gene:	il4i1 / 337166	ZFINID:	ZDB-GENE-030131-9110	Length:	504	Species:	Danio rerio

Alignment Length:	599	Identity:	126/599 - (21%)
Similarity:	196/599 - (32%)	Gaps:	211/599 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KCLE-------LQCT---IAISKFPMHNIQLPGMSGAQRNQDRKIVVIGAGASGVACATKLLELG 66
            |||:       |:.|   :..:|.|.|                 ::::||||:|:. |.|.||..
Zfish    26 KCLQDSDYDYLLKITEQGLPPTKTPKH-----------------VLIVGAGAAGLT-AAKFLEDA 72

  Fly    67 FQNVLVVEAEDRLGGRIHT----------------IPFADNVIDLGAQ----------------- 98
            ...|.::||.||:||||.|                ||....::...||
Zfish    73 GHKVTIIEASDRIGGRIQTFRNGREGWYAELGAMRIPSFHRILLAVAQKLSLKLGKFVQDDPNTY 137

  Fly    99 -WCHGERDNIVYELTRKQDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLE 162
             :.:|||..   ..|.||:.::|..  |||.     :..|....|..:..|..:..|      |.
Zfish   138 YYINGERHK---TYTVKQNPDVLNY--PVYN-----QERGKNASELFNIALSKLQDD------LH 186

  Fly   163 LRHCSGSLGSYLTNKFYDTLRRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVSGRGYLDYW 227
            ...|...|.:|                 |:....|:.||....              .||.|
Zfish   187 KMGCEKMLNTY-----------------DSYSVKEYLVNVANL--------------SRGAL--- 217

  Fly   228 ECEGDILLNWKDKGYVELLRLLMRSREL-----------------NVEHGVLEQRLLLGTRVVKI 275
            ...||: ||.....|..|..:|....::                 |..:.||...:|:.::|..|
Zfish   218 RMIGDV-LNENSFYYTALTEMLYIQSDISDDQQYFEFLGGFETFPNAFYSVLNATILMNSKVQAI 281

  Fly   276 NWNRNDGRVELQ-------MSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAF 333
            :..::...|..|       |:|   ...|:|:||   ...|......|.|.|..:|..|:..:.:
Zfish   282 SQTQDGVTVSYQDWRNLGEMTN---ITGDYVLVT---STAKATLFFDFNPPLSADKMEALRSVHY 340

  Fly   334 GTVNKIFVEFPEAFWPEDWTGFTMLWRDEDLDDIR-GTSRAWLEDVFGFYRVSYQP-----RILA 392
            .:..|:.:.|.:.||..:             |.|: |.|...|...|.:|.....|     .|||
Zfish   341 SSSTKVVLSFSQKFWKNN-------------DGIKGGKSITDLPSRFIYYPSHEFPGITGGAILA 392

  Fly   393 GWITNESGRHMETLPVDEVQAGVMYLFRRFLRWKIPDPANFRTSAWYTND--NFRGSYSYRSMDT 455
            .:.|::....::||..:|::|.|:                        ||  ...|.:      .
Zfish   393 SYTTSDDATLLQTLDEEELKAVVL------------------------NDLVKIHGEH------I 427

  Fly   456 EQLGTGAR-------ELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFAGEASSEHYYSTVH 513
            .||.||..       ..||....:.|..:....|......:.|     :.||||     :.:..|
Zfish   428 RQLCTGGAVKKWGMDPYSHGAFAIFTPFQMRDYSASLVQNEGR-----IYFAGE-----HTARPH 482

  Fly   514 GAVEAGWREARRLA 527
            |.:|...:.|.|.|
Zfish   483 GWIETAMKSALRAA 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	26/91 (29%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	112/544 (21%)
il4i1	XP_009289997.1	YobN	69..501	CDD:224152	111/538 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840