DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7737 and Paox

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001099781.1	Gene:	Paox / 293589	RGDID:	1561125	Length:	531	Species:	Rattus norvegicus

Alignment Length:	529	Identity:	147/529 - (27%)
Similarity:	223/529 - (42%)	Gaps:	84/529 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 SGVACATKL-LELGFQNVLVVEAEDRLGGRIHTIPFA--------DNVIDLGAQWCHG-ERDNIV 108
            ||..|..|| |.|.|...|.  .:|..|......|.|        ..|::|||.|.|| .:.|.|
  Rat    38 SGWVCEIKLGLGLSFNPTLT--QQDWKGRWSSLEPSAGQGFVRKRSGVVELGAHWIHGPSQGNPV 100

  Fly   109 YELTRK----------QDEELLESTGPV-YENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLE 162
            ::|..:          ::.:|:|:.|.| ..:..|..|...|..|.|:.......|  |:.|..|
  Rat   101 FQLAAEFGLLGEKELSEENQLVETGGHVALPSVSCTSSGTSVSLELVTEMGSLFYG--LIDRTRE 163

  Fly   163 LRHCS----GSLGSYLTNKFYDTL---RRPENSD-IDAEVASEFFVNYQKFENSVEASDTLEQVS 219
            ..:.|    .|:|.:|..:....:   ...||:. :...|.:.||    ..|..|..:.:::.|:
  Rat   164 FLNESETPMASVGEFLKKEISQQVANWTEDENTKRLKLAVLNTFF----NIECCVSGTHSMDLVA 224

  Fly   220 GRGYLDYWECEG-DILLNWKDKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVK-INWNRN-- 280
            ...:.:|....| |..|:   .||..|...::.|         |.:.:::..:.|| |:||.:
  Rat   225 LAPFGEYTVLPGLDCTLS---GGYQGLTNCILAS---------LPKEVMVFDKPVKTIHWNGSFQ 277

  Fly   281 ----DGR---VELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNK 338
                .|.   |.::..:|....|.||:|||.||.||:.....|||.||.:|..||..|.|||.||
  Rat   278 EAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIRKLGFGTNNK 342

  Fly   339 IFVEFPEAFWPEDWTGFTMLWRDED--LDDIRGTSRAWLEDVFGFYRV-SYQ-PRILAGWITNES 399
            ||:||.|.||..|.....::|.|..  .|........|.:.:.||..: |:: ..:|..:|....
  Rat   343 IFLEFEEPFWEPDCQFIQVVWEDTSPLQDSPLSLQDTWFKKLIGFLVLPSFESSHVLCAFIAGLQ 407

  Fly   400 GRHMETLPVDEVQAGVMYLFRRFL-RWKIPDPANFRTSAWYTNDNFRGSYSYRSMDTEQLGTGAR 463
            ...||||..:||...:..:.||.. ..::|...:...|.|::....||||||.::.:  .|....
  Rat   408 SEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPYTRGSYSYVAVGS--TGDDLD 470

  Fly   464 ELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFAGEASSEHYYSTVHGAVEAGWREARRLAQ 528
            .::.||....|..:..                 |.|||||:...:|||.|||:.:|||||.||..
  Rat   471 LMAQPLPADGTGTQLQ-----------------VLFAGEATHRTFYSTTHGALLSGWREADRLIG 518

  Fly   529 FYGISVSRS 537
            .:.....:|
  Rat   519 LWDSQAEQS 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	20/61 (33%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	144/516 (28%)
Paox	NP_001099781.1	Amino_oxidase	77..517	CDD:279874	132/476 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343424
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.650