Protein Alignment CG7737 and PAOX

DIOPT Version :9

• Sequence 1: NP_001286308.1
• Gene: CG7737 / 36174
• FlyBaseID: FBgn0033584
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_690875.1
• Gene: PAOX / 196743
• HGNCID: 20837
• Length: 511
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 151/533 - (28%)
• Similarity: 237/533 - (44%)
• Gaps: 82/533 - (15%)

  Fly    45 KIVVIGAGASGVACATKLL-ELGFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHG-ERDNI 107
            :::|:|.|.:|:..|.:|. ...|.::.|:||..|.||||.:......|:::||.|.|| .|.|.
Human    15 RVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNP 79

  Fly   108 VYELTRK----------QDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLE 162
            |::|..:          |:.:|:|:.|.|........|:|..|..::.:.: |.:...|:.:..|
Human    80 VFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEM-ATLFYGLIDQTRE 143

  Fly   163 LRHCS----GSLGSYLTNKFYDTL----RRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVS 219
            ..|.:    .|:|.||..:....:    ...|...:...|.:.||    ..|..|..:.:::.|:
Human   144 FLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFF----NLECCVSGTHSMDLVA 204

  Fly   220 GRGYLDYWECEG-DILLNWKDKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVKINWNRN--- 280
            ...:.:|....| |...:   |||..|...:|.:        :.|..::....|..|:||.:
Human   205 LAPFGEYTVLPGLDCTFS---KGYQGLTNCMMAA--------LPEDTVVFEKPVKTIHWNGSFQE 258

  Fly   281 ---DGR---VELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNKI 339
               .|.   |.::..:|:...|.||:|||.||.|::.....|:|.||.||..||..:.|||.|||
Human   259 AAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKI 323

  Fly   340 FVEFPEAFWPEDWTGFTMLWRD----ED----LDDIRGTSRAWLEDVFGFYRVS--YQPRILAGW 394
            |:||.|.||..|.....::|.|    ||    |.|      ||...:.||..:.  ....:|.|:
Human   324 FLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQD------AWFRKLIGFVVLPAFASVHVLCGF 382

  Fly   395 ITNESGRHMETLPVDEVQAGVMYLFRRFL-RWKIPDPANFRTSAWYTNDNFRGSYSYRSMDTEQL 458
            |.......||||..:||...:..:.||.. ..::|.|.:...|.|::....||||||.::.:  .
Human   383 IAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGS--T 445

  Fly   459 GTGARELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFAGEASSEHYYSTVHGAVEAGWREA 523
            |.....|:.||..            |.|..|.:     :.|||||:...:|||.|||:.:|||||
Human   446 GGDLDLLAQPLPA------------DGAGAQLQ-----ILFAGEATHRTFYSTTHGALLSGWREA 493

  Fly   524 RRLAQFYGISVSR 536
            .||...:...|.:
Human   494 DRLLSLWAPQVQQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	22/59 (37%)
		Amino_oxidase	54..526	CDD:279874	145/512 (28%)
PAOX	NP_690875.1	PLN02568	14..497	CDD:215308	149/522 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.650