Protein Alignment CG7737 and lsd-1

DIOPT Version :10

• Sequence 1: NP_001286308.1
• Gene: CG7737 / 36174
• FlyBaseID: FBgn0033584
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_510000.2
• Gene: lsd-1 / 181369
• WormBaseID: WBGene00011615
• Length: 737
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 149/615 - (24%)
• Similarity: 235/615 - (38%)
• Gaps: 167/615 - (27%)

  Fly    22 ISKFPMHNIQ--LPGMSGAQRNQDRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIH 84
            :|:|.|.||.  .|........:.:.:|||||||:|:|.||:||..|| :|.||||....|||:.
 Worm   151 LSRFGMINIGFFFPKTELVNNMEKKFVVVIGAGAAGIAAATQLLTFGF-DVAVVEASGLTGGRVR 214

  Fly    85 TIPFADNVIDLGAQWCHGERDNIVYELTRKQDEELLES---TGPVYENY----ECVRSNGDVVPE 142
            ::...           |||......:..|..||.::.:   ..|:.||.    ..|.|.|..||
 Worm   215 SLISK-----------HGELIETGCDSLRNLDESVITTLLHQVPLNENIMSENTIVFSKGKYVP- 267

  Fly   143 EVSSRLKAIVGDSLVTRQLELRHCS------GSLGSYLTNK------------------------ 177
              .:|...|.| .....:..|.|.|      |..|.|::.:
 Worm   268 --VARCHVING-LYANLKAGLAHASHGPEQRGENGLYISRQQAYENYFNMIERSTLLSYYNFAKE 329

  Fly   178 ----------FYDTLR---------------RPENSD-------IDAEVA-SEFFVNYQKFENSV 209
                      .|:.|:               .|.:.:       ||.|.| .:|....::||...
 Worm   330 KVNLNAERKHLYEVLKTNRLTALLAEQKLKNTPPSDELLLKSLQIDIEKAIRQFDEACERFEICE 394

  Fly   210 EASDTLEQ-------VSGRGYLDYWECEGDILLNWKDKGYVELL----------RLLMRSRELNV 257
            |....||:       :....::.|     :.||.::::.:...|          .|.::|:...|
 Worm   395 ERIADLEKNPRCKQSMHPNDFIHY-----NFLLGFEERLFGAQLEKVQFSCNVNELKLKSQVARV 454

  Fly   258 EHGVL--------EQRLLL--GTRVVKINWNRNDGRV-ELQMSNGETCI--ADHVVVTVSLGVLK 309
            :.|:.        |:::.:  ..||::|:...:|..: :|:..:|...|  ||:||.|:.:||||
 Worm   455 QEGLAQVLINVANERKVKIHHNQRVIEIDTGSSDAVILKLRKPDGSVGILNADYVVSTLPIGVLK 519

  Fly   310 -----DQHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPEDWTGFTMLWRDEDLDDIRG 369
                 |:...:|.|.||..|..||..|..|.:|||...|...||||....|.::   .|....|.
 Worm   520 KTIIGDERAPVFRPPLPKSKFAAIRSLGNGLINKIVFVFETRFWPESINQFAIV---PDKISERA 581

  Fly   370 TSRAWLEDVFGFYRVSYQP--RILAGWITNESGRHMETLPVDEVQAGVMYLFRRFLRWKIPDPAN 432
            ....|          |..|  |.|......|:..|  ..||.|:....:.:.:...: ..|.|.:
 Worm   582 AMFTW----------SSLPESRTLTTHYVGENRFH--DTPVTELITKALEMLKTVFK-DCPSPID 633

  Fly   433 FRTSAWYTNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIV 497
            ...:.|:|::...|:.::.|:.||.....|  |..||                   ::|..:|.|
 Worm   634 AYVTNWHTDELAFGTGTFMSLRTEPQHFDA--LKEPL-------------------KTRDGKPRV 677

  Fly   498 QFAGEASSEHYYSTVHGAVEAGWREARRLA 527
            .||||.:|...:.|:.||..:|.|.|..||
 Worm   678 FFAGEHTSALEHGTLDGAFNSGLRAAADLA 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:396255	134/578 (23%)
lsd-1	NP_510000.2	SWIRM	80..158	CDD:461307	3/6 (50%)
		Amino_oxidase	191..706	CDD:396255	131/572 (23%)