DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7737 and Il4i1b

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001164495.1	Gene:	Il4i1b / 100328588	MGIID:	5439399	Length:	638	Species:	Mus musculus

Alignment Length:	596	Identity:	138/596 - (23%)
Similarity:	211/596 - (35%)	Gaps:	155/596 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NQDRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFADN----VIDLGAQWCH 101
            ::.:|:||:|||.:|:..|..|.:.| ..|.::||::|:||||.|  |.|.    :.:|||....
Mouse    64 SKPQKVVVVGAGVAGLVAAKMLSDAG-HKVTILEADNRIGGRIFT--FRDEKTGWIGELGAMRMP 125

  Fly   102 GERDNIVYELTRKQDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLELRHC 166
            ... .|:::|.|.....|.:.|  .|:.......:...:...|..::...:|.:|..|  |..|.
Mouse   126 SSH-RILHKLCRTLGLNLTQFT--QYDENTWTEVHNVKLRNYVVEKMPEKLGYNLNNR--ERGHS 185

  Fly   167 SGSLGSYLTNKFYDTLRRPENSDIDAEVASEFFVNYQKFENSVE-----------ASDTLEQVSG 220
            ...:.....||.:..|:.     :..:.|...|..:...|..:|           ..|.:.: .|
Mouse   186 PEDIYQMALNKAFKDLKA-----LGCKKAMNKFNKHTLLEYLLEEGNLSRPAVQLLGDVMSE-EG 244

  Fly   221 RGYLDYWE------CEGDILLNWKDKGYVELL-RLLMRSRELNVEHGVLEQRLLLGTRVVKINWN 278
            ..||.:.|      |..|.|...:..|..:|| |.|:.|         |...|||...||.|...
Mouse   245 FFYLSFAEALRAHACLSDRLRYSRIVGGWDLLPRALLSS---------LSGALLLNAPVVSITQG 300

  Fly   279 RNDGRVELQMS--NGETCIADHVVVTVSLGVLKDQHLRL-FEPQLPVEKQRAIDGLAFGTVNKIF 340
            |||.||.:..|  :.:|..||.|::|.|...|:    |: |.|.|..::|.|:..|.:...:|:|
Mouse   301 RNDVRVHIATSLHSEKTLTADVVLLTASGPALQ----RITFSPPLTRKRQEALRALHYVAASKVF 361

  Fly   341 VEFPEAFWPED--------------------------------WTG----FTMLWRDEDLD---- 365
            :.|...||.|:                                |:.    |..|..|:.|.
Mouse   362 LSFRRPFWHEEHIEGGHSNTDRPSRLIFYPAQGEGSLLLASYTWSDAAAPFAGLSTDQTLRLVLQ 426

  Fly   366 --------------DIRGTSRAWLEDVFGFYRVSYQPRILAGWITNES--GRHME---------- 404
                          |.||..:.|.||          |....|::....  ||..|
Mouse   427 DVAALHGPVVFRLWDGRGVVKRWAED----------PHSQGGFVVQPPLYGREAEDYDWSAPFGR 481

  Fly   405 --------TLPVDEVQAGVMYLFRRFLR------WKIPDPANFRTSAWYTNDNFRGSYSYRSMDT 455
                    .||...|:..|....|..:|      :...||.....:  |...|:...|.......
Mouse   482 IYFAGEHTALPHGWVETAVKSGLRAAVRINNNYGYGEVDPQMMEHA--YAEANYLDQYPEGERPE 544

  Fly   456 EQ-----LGTGARELSHPLTVVATTPEKDKDSEDEAWQQSRCD---RPIVQFAGEASSEHYYS-- 510
            ||     :....:|.||...:|.|:||..:.:..||..:.:..   ..:.|..|.|....|.|
Mouse   545 EQQAREEVSPDEQEPSHKHLLVETSPEGQQHAFVEAIPELQGHVFVETVPQEKGHAHQNIYPSEH 609

  Fly   511 -TVHGAVEAGW 520
             .|||.|...|
Mouse   610 VQVHGEVIPEW 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	22/61 (36%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	132/583 (23%)
Il4i1b	NP_001164495.1	Amino_oxidase	83..511	CDD:279874	104/464 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840