DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7737 and XB5760632

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	XP_031748369.1	Gene:	XB5760632 / 100145496	XenbaseID:	XB-GENE-5760633	Length:	556	Species:	Xenopus tropicalis

Alignment Length:	568	Identity:	169/568 - (29%)
Similarity:	263/568 - (46%)	Gaps:	85/568 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YGKWTVIKLKCLELQCTIAISKFPMHNIQLPGMSGAQ-RNQDRKIVVIGAGASGVACATKLLELG 66
            ||..:..|.:.......:::..|      |..|.|.. .:|..::|::|||.:|:..||.|.:.|
Frog    30 YGGASTSKGRSSSWPSRVSLDTF------LSSMDGVYLGSQPLRVVIVGAGFAGLGAATTLAKHG 88

  Fly    67 FQNVLVVEAEDRLGGRIHT-IPFADNVIDLGAQWCHGERDNIVYELTRKQDEELLESTGPVYENY 130
            .::::::||.||.|||:.| .|..|..::|||.|.||:.||.:|::.:  ::.||...|  :...
Frog    89 VRDLVILEASDRPGGRVLTHKPTGDPALELGATWIHGQTDNPLYQMAK--EKGLLADDG--FNMV 149

  Fly   131 EC-----------VRSNGDVVPEEVSSRLKAIVGDSL--VTRQLELRHC-SGSLGSYLTNKF-YD 180
            .|           ...:|.::|.....::....|.::  :.:|.....| |.|:|.||..:| ..
Frog   150 TCQPISVTPQDYFFSEDGKLLPANEVDQVTCFFGQTMAKINQQDFKPECASWSVGKYLDREFAAS 214

  Fly   181 TLRRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVSGRGYLDYWECEGDILLNWKDKGYVEL 245
            .:.:.|:|:       ..|...::.|...||.:::.:.|......|...||....:....||..|
Frog   215 AIAKSESSE-------GVFEWCKRIECVDEACNSMYEFSLSQLGLYTALEGPFFNSLGSGGYQAL 272

  Fly   246 LRLLMRSRELNVEHGVLEQRLLLGTRVVK-INW------NRNDGRVELQMSNGETCIADHVVVTV 303
            |.:|:..         |....|...:.|| :.|      :::...|.:...:||...||||:|||
Frog   273 LNVLLDQ---------LPPNSLRCCKPVKCVQWEGSPPTSKSKPPVVVLCEDGEAFPADHVIVTV 328

  Fly   304 SLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPEDWTGFTMLWR-------- 360
            |||.||::...||:|.||..|..|::.|.||||.|||:||.|.|||:|..|..::|:
Frog   329 SLGCLKERASSLFDPPLPQGKMEAVERLGFGTVAKIFLEFSEPFWPDDCAGIQLVWQQGPESPEG 393

  Fly   361 -----DEDLDDIRGTSRAWLEDVFGFYRVSYQPRILAGWITNESGRHMETLPVDEVQAGVMYLFR 420
                 .|||  :|.   .|.:.:.||..|.....||.||||..:..||||||..||....:.|.:
Frog   394 YTAHNQEDL--LRS---EWYKKIGGFDCVPLHRSILCGWITGLAAEHMETLPEKEVGDICVRLLK 453

  Fly   421 RFLRWKIPDPANFRTSAWYTNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPEKDKDSEDE 485
            :|..|.:.:......|.|:||...||||:                :.|:.|.|...:|..:....
Frog   454 QFTGWPVSELRGVLRSTWHTNPYTRGSYT----------------NVPVGVDAVKEQKALEEPLP 502

  Fly   486 AWQQSRCDRPI-VQFAGEASSEHYYSTVHGAVEAGWREARRLAQFYGI 532
            :..|.|..||: |.|||||:..::|:|.|||...|.|||.|:...|.|
Frog   503 STHQKRRLRPLQVLFAGEATHTNFYTTTHGAYLTGVREAERILGHYEI 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	24/58 (41%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	154/508 (30%)
XB5760632	XP_031748369.1	PLN02568	91..548	CDD:215308	150/497 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77187
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920