DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx7 and VAM3

DIOPT Version :9

Sequence 1:	NP_730632.1	Gene:	Syx7 / 36173	FlyBaseID:	FBgn0267849	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_568671.1	Gene:	VAM3 / 834730	AraportID:	AT5G46860	Length:	268	Species:	Arabidopsis thaliana

Alignment Length:	299	Identity:	85/299 - (28%)
Similarity:	138/299 - (46%)	Gaps:	56/299 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQHMENG-------LSGGGGGGLSEIDFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSP 58
            |..|.:|:|       .:||.         |...|.:|:.|.::...|||.||:||.|.||:|:|
plant     1 MSFQDLESGRGRSTRKFNGGR---------QDSTQAVASGIFQINTGVSTFQRLVNTLGTPKDTP 56

  Fly    59 ELKKQLHQIMTYTNQLVTDTNNQINEVDKCKER-----HLKIQRDRLVDEFTAALTAFQSVQRKT 118
            ||:::||:...:..|||.||:.::.|..:...:     ..||...:|..:|.|.|..||..|:..
plant    57 ELREKLHKTRLHIGQLVKDTSAKLKEASETDHQSGVNPSKKIADAKLARDFQAVLKEFQKAQQTA 121

  Fly   119 ADIEKTALRQARGDSYNIARPPGSSRTGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEEQA 183
            |:.|.|         |....|..:.   .|:.:|.:.|            |..:|:.|.|..::.
plant   122 AERETT---------YTPFVPQSAL---PSSYTAGEVD------------KVPEQRAQLQESKRQ 162

  Fly   184 DL-----------QALEEQEQVIRELENNIVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFV 237
            :|           ..:||:||.|:|:...|..||||:|.|..||.:||:.:|.|.:.::.:....
plant   163 ELVLLDNEIAFNEAVIEEREQGIQEIHQQIGEVNEIFKDLAVLVNDQGVMIDDIGTHIDNSRAAT 227

  Fly   238 SQGTENLRKASSYRNKVRKKKLILVGILSAVLLAIILIL 276
            |||...|.:|:..:........:|:.|...|||.:|::|
plant   228 SQGKSQLVQAAKTQKSNSSLTCLLLVIFGIVLLIVIIVL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx7	NP_730632.1	Syntaxin_2	30..126	CDD:291208	36/100 (36%)
		COG5325	<97..276	CDD:227635	50/189 (26%)
		SNARE	188..247	CDD:304603	23/58 (40%)
VAM3	NP_568671.1	Syntaxin_2	28..128	CDD:405246	36/108 (33%)
VAM3	NP_568671.1	SNARE_Qa	178..236	CDD:277193	23/57 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I3465
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37823
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2079
OMA	1	1.010	-	-		QHG53539
OrthoDB	1	1.010	-	-		D1204812at2759
OrthoFinder	1	1.000	-	-		FOG0000747
OrthoInspector	1	1.000	-	-		otm3548
orthoMCL	1	0.900	-	-		OOG6_102289
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X633
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840