Protein Alignment Syx7 and STX1A

DIOPT Version :10

• Sequence 1: NP_730632.1
• Gene: Syx7 / 36173
• FlyBaseID: FBgn0267849
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_004594.1
• Gene: STX1A / 6804
• HGNCID: 11433
• Length: 288
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 63/275 - (22%)
• Similarity: 121/275 - (44%)
• Gaps: 49/275 - (17%)

  Fly    22 DFQRLAQIIATSIQKVQQNVSTMQRMVNQ-LNTPQDSPELKKQLHQIMTYTNQLVTDTNNQINEV 85
            :|....:.|...|.|:.:||..::|..:. |.:|....:.|::|.::|       :|.....|:|
Human    32 EFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELM-------SDIKKTANKV 89

  Fly    86 -DKCKERHLKIQRDRLVDEFTAAL----TAFQSVQRKTADIEKTALRQARGDSYNIARPPGSSR- 144
             .|.|.....|:::..::..:|.|    |...::.||..::.         ..||..:.....|
Human    90 RSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM---------SEYNATQSDYRERC 145

  Fly   145 ----------TGSSNSSASQQD-----NNSFFEDNFFNRKSNQQQMQTQMEEQADLQALEEQEQV 194
                      ||.:.:|...:|     |.:.|.....        |.:.:.:|| |..:|.:...
Human   146 KGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGII--------MDSSISKQA-LSEIETRHSE 201

  Fly   195 IRELENNIVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKL 259
            |.:|||:|..:::::..:..||..||..:|.||..||....:|.:...:.:||..|::|.|:||:
Human   202 IIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKI 266

  Fly   260 ILVGILSAVLLAIIL 274
            ::  |:..|:|.|::
Human   267 MI--IICCVILGIVI 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx7	NP_730632.1	Syntaxin_2	30..123	CDD:464199	22/98 (22%)
		COG5325	<97..276	CDD:227635	45/198 (23%)
		SNARE	188..247	CDD:473982	16/58 (28%)
STX1A	NP_004594.1	SynN	30..181	CDD:238105	32/164 (20%)
		SNARE_syntaxin1	191..259	CDD:277233	21/68 (31%)