DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx7 and stx12

DIOPT Version :9

Sequence 1:	NP_730632.1	Gene:	Syx7 / 36173	FlyBaseID:	FBgn0267849	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_998883.1	Gene:	stx12 / 407856	XenbaseID:	XB-GENE-974475	Length:	267	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	89/270 - (32%)
Similarity:	155/270 - (57%)	Gaps:	30/270 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSPELKKQLHQIMTYTNQLVTDTNNQINE-- 84
            ||..:.|..:.::|::..|.:.::.::|||.|.|||.:|::.|.||...||.|..:||..:.:
Frog    13 DFNSIIQTCSGNVQRITNNTAQIRTLLNQLGTSQDSTKLQQNLQQIQHSTNVLAKETNTYLKDLA 77

  Fly    85 -----VDKCKERHLKIQRDRLVDEFTAALTAFQSVQRKTADIEKTALRQARGDSYNIARPPGSSR 144
                 :...::|..|:|::||:::|:|||..||::||:.:..||..:.:|              |
Frog    78 SVPTPLSPAEQRQQKLQKERLMNDFSAALNHFQAIQRQVSTKEKETVARA--------------R 128

  Fly   145 TGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEE----QADLQALEEQEQVIRELENNIVGV 205
            .||..|:..:|.......   |:...:..|:|:|.||    :.||:.::|:|..|::||.:|:.|
Frog   129 AGSRLSADERQKEEQLVS---FDNNEDWNQLQSQDEEFAVTEEDLELIKERESAIQKLEADILDV 190

  Fly   206 NEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLILVGILSAVLL 270
            |:|:|.|..::::||..:||||:.||...:.|.:|||.|::|:.|:.|.|||..|||  |:..:.
Frog   191 NQIFKDLAVMIHDQGEMIDSIEANVESAEVHVERGTEQLQRAAYYQKKSRKKICILV--LALAIA 253

  Fly   271 AIILILVFQF 280
            |:||.|:..|
Frog   254 AVILGLIIYF 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx7	NP_730632.1	Syntaxin_2	30..126	CDD:291208	33/102 (32%)
		COG5325	<97..276	CDD:227635	63/182 (35%)
		SNARE	188..247	CDD:304603	24/58 (41%)
stx12	NP_998883.1	Syntaxin_2	22..124	CDD:373109	33/101 (33%)
stx12	NP_998883.1	SNARE_syntaxin12	173..239	CDD:277229	26/65 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I8900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4205
OMA	1	1.010	-	-		QHG53539
OrthoDB	1	1.010	-	-		D1204812at2759
OrthoFinder	1	1.000	-	-		FOG0000747
OrthoInspector	1	1.000	-	-		otm47591
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X633
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080