Protein Alignment Syx7 and STX2

DIOPT Version :10

• Sequence 1: NP_730632.1
• Gene: Syx7 / 36173
• FlyBaseID: FBgn0267849
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: XP_047284447.1
• Gene: STX2 / 2054
• HGNCID: 3403
• Length: 320
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 65/276 - (23%)
• Similarity: 121/276 - (43%)
• Gaps: 44/276 - (15%)

  Fly    22 DFQRLAQIIATSIQKVQQNVSTMQRMVNQ---LNTPQDSPELKKQLHQIMTYTNQLVTDTNNQIN 83
            ||....:.|..||.|:.|.|..:::  |.   |:.|....::|::|..:    |:.:..|.|:|.
Human    63 DFFHQVEEIRNSIDKITQYVEEVKK--NHSIILSAPNPEGKIKEELEDL----NKEIKKTANKIR 121

  Fly    84 EVDKCKER-------------HLKIQRDR---LVDEFTAALTAFQSVQRKTADIEKTALRQ-ARG 131
            ...|..|:             .|:|:|.:   |..:|..|:..:...|        |..|: ::|
Human   122 AKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQ--------TLFRERSKG 178

  Fly   132 DSYNIARPPGSSRTGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEEQADLQALEEQEQVIR 196
            .........|.:.|........:....|.|..:..:        .:|:..|| |..:|.:.:.|.
Human   179 RIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIIS--------DSQITRQA-LNEIESRHKDIM 234

  Fly   197 ELENNIVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLIL 261
            :||.:|..::|::..:...|..||..:::||..|...:.:|....|..:||..|::|.|:||.|:
Human   235 KLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWII 299

  Fly   262 VGILSAVLLAIILILV 277
            :.: |.||:|||.:::
Human   300 IAV-SVVLVAIIALII 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx7	NP_730632.1	Syntaxin_2	30..123	CDD:464199	24/111 (22%)
		COG5325	<97..276	CDD:227635	44/182 (24%)
		SNARE	188..247	CDD:473982	14/58 (24%)
STX2	XP_047284447.1	Syntaxin	63..258	CDD:459942	44/217 (20%)
		SNARE	259..310	CDD:461727	17/51 (33%)