DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9084 and Plscr3

DIOPT Version :9

Sequence 1:	NP_001260884.1	Gene:	CG9084 / 36172	FlyBaseID:	FBgn0033582	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001161969.1	Gene:	Plscr3 / 70310	MGIID:	1917560	Length:	296	Species:	Mus musculus

Alignment Length:	254	Identity:	74/254 - (29%)
Similarity:	110/254 - (43%)	Gaps:	41/254 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PRPEAPRIPLP-VPIATVTGSRTLIPLSGYDCLADLPSVHIEQTFELNDVRLPFAALTGVSSENR 103
            |.|.||.:||| ||             .|.:.|..:..:.|.|..|..:..|      |..:.|.
Mouse    61 PGPPAPFVPLPGVP-------------PGLEFLVQIDQILIHQKAERVETFL------GWETCNM 106

  Fly   104 YVVRSPLGDAIFAANESSTEKNRLLWGAGRPFQMHLLDKTHQEALVFRKKLAMGSMCCQA--KSL 166
            |.:||..|..:..|.|.|....||..||.|||::.|.|...:|.|...:.|..|..||..  :.:
Mouse   107 YELRSGTGQQLGQAAEESNCCARLCCGARRPFRIRLADPGDREVLRLLRPLHCGCSCCPCGLQEM 171

  Fly   167 EIWIPPGNLLGKVVQSPTFMQPEFFIEDESTGQLTFCVEGP---VGLGFCCFSLPKDCYFKIHSG 228
            |:..|||..:|.|:|:.....|:|.|.| :..|....|.||   .|.|       .|..|::.:.
Mouse   172 EVQAPPGTTIGHVLQTWHPFLPKFSILD-ADRQPVLRVVGPCWTCGCG-------TDTNFEVKTK 228

  Fly   229 GNMRA--SIDHKWLASKSQYTTN-----IYFSDAKLTAKERALILGSAFLLEYLFFQTR 280
            ...|:  .|..:|.....:..|:     :.| ...|..|.:|::||:.||::|:||:.|
Mouse   229 DESRSVGRISKQWGGLLREALTDADDFGLQF-PVDLDVKVKAVLLGATFLIDYMFFEKR 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9084	NP_001260884.1	LOR	66..277	CDD:295149	62/222 (28%)
Plscr3	NP_001161969.1	Proline-rich domain (PRD). /evidence=ECO:0000250\|UniProtKB:O15162	1..58
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
		SH3-binding 1. /evidence=ECO:0000255	7..15
		PPxY motif. /evidence=ECO:0000255	15..18
		SH3-binding 2. /evidence=ECO:0000255	21..27
		SH3-binding 3. /evidence=ECO:0000255	66..71		2/4 (50%)
		Scramblase	69..285	CDD:252175	69/243 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920