DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9084 and Plscr4

DIOPT Version :9

Sequence 1:	NP_001260884.1	Gene:	CG9084 / 36172	FlyBaseID:	FBgn0033582	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_848826.1	Gene:	Plscr4 / 235527	MGIID:	2143267	Length:	326	Species:	Mus musculus

Alignment Length:	284	Identity:	68/284 - (23%)
Similarity:	115/284 - (40%)	Gaps:	47/284 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VAQQPSL---------SEPRVYD-SHISITSQPRPEAPRI----PLPVPIATVTGSRTLIPLSGY 68
            :.|||..         :.|..|. ....:|:||   ||.:    |.|||...          .|.
Mouse    58 IPQQPGAIPLYHPTGGTHPIQYQPGKYPVTNQP---APIMWMAGPAPVPNCP----------PGL 109

  Fly    69 DCLADLPSVHIEQTFELNDVRLPFAALTGVSSENRYVVRSPLGDAIFAANESSTEKNRLLWGAGR 133
            :.||.|.::|:.|..|      |...:|...:.|||.:::.:...::...|.:.:..|..:...|
Mouse   110 EYLAQLDNIHVLQHVE------PLELMTRFETNNRYDIKNNIDQMVYIVTEDTDDFTRNAYRNLR 168

  Fly   134 PFQMHLLDKTHQEALVFRKKLAMGSMC----CQAKSLEIWIPPGNLLGKVVQSPTFMQPEFFIED 194
            ||.:.:.|...:|.:..::.......|    |..:.||:..|||..:|.|.:.....:..:.|::
Mouse   169 PFVLRVTDCLGREIMTMQRPFRCTCCCFCCPCARQELEVQCPPGVTIGFVAEHWNLCRASYSIQN 233

  Fly   195 ESTGQLTFCVEGPVGLGFCCFSLPKDCYFKIHS--GGNMRASIDHKWLASKSQYTTNIYFS---D 254
            |....: ..|.||.....|    ..|..|:|:|  |.:...||..||....|......:|.   .
Mouse   234 EKKESM-MRVRGPCATYGC----GSDSVFEINSLDGVSNIGSIIRKWNGFLSTMVNADHFEIRFP 293

  Fly   255 AKLTAKERALILGSAFLLEYLFFQ 278
            ..|..|.:|:|.||.||:::::|:
Mouse   294 LALDVKMKAMIFGSCFLIDFMYFE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9084	NP_001260884.1	LOR	66..277	CDD:295149	53/219 (24%)
Plscr4	NP_848826.1	Proline-rich domain (PRD). /evidence=ECO:0000250	1..94		10/38 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		SH3-binding 1. /evidence=ECO:0000255	18..25
		DAZAP2	27..>113	CDD:287943	15/67 (22%)
		PPxY motif. /evidence=ECO:0000255	30..33
		SH3-binding 2. /evidence=ECO:0000255	41..49
		SH3-binding 3. /evidence=ECO:0000255	94..102		1/7 (14%)
		Scramblase	96..318	CDD:252175	58/243 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920