Protein Alignment shn and HIVEP3

DIOPT Version :10

• Sequence 1: NP_001260883.1
• Gene: shn / 36171
• FlyBaseID: FBgn0003396
• Length: 2587
• Species: Drosophila melanogaster
• Sequence 2: NP_078779.2
• Gene: HIVEP3 / 59269
• HGNCID: 13561
• Length: 2406
• Species: Homo sapiens
• Alignment Length: 36
• Identity: 10/36 - (27%)
• Similarity: 18/36 - (50%)
• Gaps: 6/36 - (16%)

  Fly    17 ETRTNSLDLLESKL------SDVNQDIYETMLCSES 46
            ||:.....:|:||.      ..|.:.:||:..|::|
Human   334 ETKRRRKRVLKSKTFVDEEGCIVTEKVYESESCTDS 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shn	NP_001260883.1	C2H2 Zn finger	486..506	CDD:275368
		zf-H2C2_2	499..523	CDD:463886
		C2H2 Zn finger	514..536	CDD:275368
		PRK12323	<1185..>1269	CDD:481241
		zf-C2H2	1816..1838	CDD:395048
		C2H2 Zn finger	1818..1838	CDD:275370
		zf-H2C2_2	1830..1855	CDD:463886
		zf-C2H2	1844..1868	CDD:395048
		C2H2 Zn finger	1846..1868	CDD:275370
		zf-C2H2_8	<2305..2352	CDD:464935
		C2H2 Zn finger	2308..2328	CDD:275368
		zf-C2H2_jaz	2333..2359	CDD:432381
		C2H2 Zn finger	2336..2358	CDD:275368
		C2H2 Zn finger	2381..2403	CDD:275368
HIVEP3	NP_078779.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..112
		ZAS1	192..242
		C2H2 Zn finger	194..214	CDD:275368
		zf-H2C2_2	207..231	CDD:463886
		No DNA binding activity or transactivation activity, but complete prevention of TRAF-dependent NF-Kappa-B activation, associates with TRAF2 and JUN. /evidence=ECO:0000250	211..1074		10/36 (28%)
		C2H2 Zn finger	222..242	CDD:275368
		Acidic 1	264..287
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..358		6/23 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	377..409
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..540
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..633
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	677..696
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	706..1115
		Acidic 2	862..883
		Nuclear localization signal. /evidence=ECO:0000255	903..909
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1268..1303
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1406..1459
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1472..1594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1692..1727
		ZAS2	1754..1806
		zf-C2H2	1754..1776	CDD:395048
		C2H2 Zn finger	1756..1776	CDD:275370
		zf-H2C2_2	1768..1793	CDD:463886
		ZnF_U1	1779..1812	CDD:197732
		C2H2 Zn finger	1784..1802	CDD:275370
		Acidic 3	1817..1872
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1818..2033
		PHA03247	<1877..2395	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2052..2113
		6 X 4 AA tandem repeats of S-P-X-[RK]	2053..2148
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2125..2151
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2224..2406