|
Fly 420 RTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQ--QLTQPT----------TVSPGIPGGAA 472
|.||. |.|....|.....:..|.|......| :...|| .:|||:.....
Human 74 RAPLV-----TGSLDGGNVPFILSPVLQPEGPGPTQVGKPAAPTLTVNIVGTLPVLSPGLGPTLG 133
Fly 473 APNPACEKSGRYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHA 537
:|... ..:|:|:|.:|...|.||||||||||:||.|||:||.||||||||:||||||.|:::|.
Human 134 SPGKV-RNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPCATCGIAFKTQSNLYKHRRTQTHL 197
Fly 538 ARARGLEVPADADDGL---SDQDAE--------------LSNSSSELPSRAGSPYEEPI------ 579
..:|.......|..|| .|:..| :...:||.|...|: ..|:
Human 198 NNSRLSSESEGAGGGLLEEGDKAGEPPRPEGRGESRCQGMHEGASERPLSPGA--HVPLLAKNLD 260
Fly 580 --NSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLGSPAAGTLPPTTADNHHSATAQHRQSIDYKP 642
....|.|.:..|.:.|.....|:.: | |.|||.| :|
Human 261 VRTEAAPCPGSAFADREAPWDSAPMAS-----P-GLPAAST----------------------QP 297
Fly 643 YKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLSIQLPLVQQPSLAHPTLSPSTQMK 707
:: :||..:.|:...|
Human 298 WR-----------------------------------------KLPEQKSPTAGKP--------- 312
Fly 708 MKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVY--------YLGQPSYYNQDTAAAIHQHAL 764
..||:||:..|::...|..|.|.:. ||.: .|:|...|....
Human 313 -----------CALQRQQATAAEKPWDAKAPEGRLRKCESTDSGYLSR-----SDSAEQPHAPCS 361
Fly 765 AIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLS 829
.:.....|.|:.:.:......|.|....|
Human 362 PLHSLSEHSAESEGEGGPGPGPGVAGAEP------------------------------------ 390
Fly 830 TFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHGS 894
.:...|.::...:::|.|::|||.|:|:|::.::
Human 391 --GAREAGLELEKKRLEERIAQLISHNQAVVDDAQL----------------------------- 424
Fly 895 NASALHANNSQNNTNAQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQ 959
:|. |..|..|: :|..::....||| :
Human 425 -----------DNV------RPRKTGLS----------------------KQGSIDLPTPYTY-K 449
Fly 960 QQQECQQQQLEPPNGVVKRNAYKPGVVMTT--------------------------PVKQQQQLP 998
.......:.|||. :|.| ||.|.:| ||.:...||
Human 450 DSFHFDIRALEPG----RRRA--PGPVRSTWTPPDKSRPLFFHSVPTQLSTTVECVPVTRSNSLP 508
Fly 999 PPPSPLPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVP-------VSSLSTSS 1056
.... .:|....::|..|.::.::|.:..| .|..|..:...:...|| |...:...
Human 509 FVEG---SRTWLEPREPRDPWSRTQKPLSPRP-GPARLGCRSGLSSTDVPSGHPRALVRQAAVED 569
Fly 1057 LAPTP----TTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGE-----GDDA---VY-- 1107
|..|| ......|.:.:||...|..............|.|.:...| ||:. :|
Human 570 LPGTPIGDALVPAEDTDAKRTAAREAMAGKGRAGGRKCGQRRLKMFSQEKWQVYGDETFKRIYQK 634
Fly 1108 --SCPICASEFR-----SADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANS 1165
:.|....:.| |..:|..........:|.:.|.....:|...:..:.:.||
Human 635 MKASPHGGKKAREVGMGSGAELGFPLQKEAAGSSGTVPTQDRRTPVHEDISAGATPE-------- 691
Fly 1166 KNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQ 1230
.|.......:|||.......:|.||......|.|..:..:||:....:|.|...
Human 692 ---------PWGNPPALEASLVTEPTKHGETVARRGDSDRPRVEEAVSSPALGGRDSPCSGSR-- 745
Fly 1231 IEALRFVDAPL--------------PSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFV 1281
:|| |:||||.| .....||..... .|:....:.|
Human 746 --------SPLVSPNGRLELGWQMPPAPGPLKG-------GDVEAPRPVWPD---PKLEGGARGV 792
Fly 1282 IEAQPA------------------------KRIKTSDL--------VVASSSQQPTSFNFSFNNQ 1314
.:.|.. |::|..|| |.|.:...||.
Human 793 GDVQETCLWAQTVLRWPSRGSGEDKLPSERKKLKVEDLHSWKQPEPVSAETPGGPTQ-------- 849
Fly 1315 NSSNSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPL-LSGGSFQDVSVKVNNET 1378
|...||:::........||| ..|.:.:..|| .||.|....||.: ...
Human 850 ------PASLSSQKQDADPGEVPGGS----------KESARQVGEPLESSGASLAAASVAL-KRV 897
Fly 1379 GSSSKERKL-MALVSGSGLLGVSSGPQHFQFPPINSITAFNP---LTLPPMSGGDKTTPV-TPIP 1438
|...|...| .|..:.:....:::.||..:.....:..||:| |.|| ...||: .|||
Human 898 GPRDKATPLHPAAPAPAEHPSLATPPQAPRVLSALADNAFSPKYLLRLP-----QAETPLPLPIP 957
Fly 1439 HVP----------GMP-------GPGSLTP--QMPLLPPPPQQLQ--LPIPSSRGRSPNRKQPSP 1482
..| |.| |.|..|| ..|...|.|.:.. |..||.......||...
Human 958 WGPRHSQDSLCSSGWPEERASFVGSGLGTPLSPSPASGPSPGEADSILEDPSCSRPQDGRKGAQ- 1021
Fly 1483 LLLGGGSGELKALS-------PFGGVQNVPSEFSRQPPTPAQR----QALQWNSKEAPKKAPFNF 1536
|||..|:..|.| |. .....|.|.:..||||... |.::.:|....:....:.
Human 1022 --LGGDKGDRMATSRPAARELPI-SAPGAPREATSSPPTPTCEAHLVQDMEGDSHRIHRLCMGST 1083
Fly 1537 L---RMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETS--PVASASASAKS 1596
| |::.:| ..|.|.::.| ..|.|||||:.| |:....
Human 1084 LARARLSGDV--LNPWVPNWEL------------------GEPPGNAPEDPSSGPLVGPD----- 1123
Fly 1597 KFLRPTSLPLKPGTFTPKRHHGITPTANTLPL-ISPETPRPSKSCVQLYLNGHAYTYLGLKCSTK 1660
|.| ||:||:|. ||.|.|. :.|..| :|.|:.|:.| ....||:
Human 1124 ----PCS-PLQPGSFL---------TALTRPQGVPPGWP-------ELALSSHSGT--SRSHSTR 1165
Fly 1661 MFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQV---MALY--DSRQRMLG---- 1716
..:.|.| |.||. |......|.....:.|.|...|.|.. :|:: .|..|..|
Human 1166 SPHSTQN-PFPSL-----KAEPRLTWCCLSRSVPLPAEQKAKAASVYLAVHFPGSSLRDEGPNGP 1224
Fly 1717 ---NGSST-AMAGSG------KLSYNLVAS---QQIVSSPSTS-------------------STS 1749
||..| ...|.| |.||..|.. |..||.|... ..:
Human 1225 PGSNGGWTWTSPGEGGPAQMSKFSYPTVPGVMPQHQVSEPEWKKGLPWRAKMSRGNSKQRKLKIN 1289
Fly 1750 SAFYQG------------PLKTPPTV--------TIAALSEANVAAKANEEAQAKKLETSPS--- 1791
...|:| .|:||..| .:..|.......:.:.|.....|:..||
Human 1290 PKRYKGNFLQSCVQLRASRLRTPTWVRRRSRHPPALEGLKPCRTPGQTSSEIAGLNLQEEPSCAT 1354
Fly 1792 --GQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFK 1854
..|..|..|..| |..|.......:......:.:...||..|:.|....|
Human 1355 SESPPCCGKEEKKE--------GDCRQTLGTLSLGTSSRIVREMDKRTVKDISPSAGEH------ 1405
Fly 1855 TKGNLTKH---------MQSKTHFKKCIELGINPGPMPP-----------------DSEFLD--- 1890
|:.|.| :||.| |:.: :|..|:|| ||...|
Human 1406 --GDCTTHSTAATSGLSLQSDT----CLAV-VNDVPLPPGKGLDLGLLETQLLASQDSVSTDPKP 1463
Fly 1891 -VDMDFDQQSSTSAGG--------------------RTSSMAGESDSDDYSDNESESSDTDESKS 1934
:..|..:.||..:.| ||..:|.|..|.:..|:...:..|..|.|
Human 1464 YIFSDAQRPSSFGSKGTFPHHDIATSVAAVCISLPVRTDHIAQEIHSAESRDHSQTAGRTLTSSS 1528
Fly 1935 -RQKEHEAARGLLSLSMTPPIPQSVSPYPQLQDT-----PLPAASPAN----------------- 1976
..|..|..|....|...|...|.:|....|:.| .:||:.|::
Human 1529 PDSKVTEEGRAQTLLPGRPSSGQRISDSVPLESTEKTHLEIPASGPSSASSHHKEGRHKTFFPSR 1593
Fly 1977 -------------SIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPE---ESKPKRSV 2020
|:||.|. ||.|....:.|......|.||....|| :|..|||:
Human 1594 GQYGCGEMTVPCPSLGSDGR--KRQVSGLITRKDSVVPSKPEQPIEIPEAPSKSLKKRSL 1651
| 
