DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and STP4

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_010235.1	Gene:	STP4 / 851512	SGDID:	S000002206	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	317	Identity:	65/317 - (20%)
Similarity:	102/317 - (32%)	Gaps:	122/317 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 RERKKEEPVDEDQCRVCTSKEELVCLF------KKQIDATPADMLLVICPNVSILPKDFMPQFIC 286
            ::|||:|      |.:|.:       |      .|....||.|.... ||             ||
Yeast   272 KQRKKKE------CPICHN-------FYANLSTHKSTHLTPEDRPHK-CP-------------IC 309

  Fly   287 TKCMGSLTIAIQLRKQLETTDQELRKRLSRSKNKVRRPR-----GYVVIDAPVTDSSEDEDELDD 346
                                    ::..:|:.:.:|..:     .::.|.|..:|::...|:.||
Yeast   310 ------------------------QRGFARNNDLIRHKKRHWKDEFMQIYARESDNNSGADDQDD 350

  Fly   347 EFKVSDVAGTTSADSDSADSDDSEKEKKKPGPRGRPRKKPLKRGTDSDGEPSSAQKKKYQPSSTA 411
                   ...|||::||.||:|                   |....|..|.:...||....|...
Yeast   351 -------TARTSANNDSDDSND-------------------KLAASSSSEETKLLKKNQLKSLYK 389

  Fly   412 SVGPFECP------NCDLTFSRKQSYVLHRKTHERIEHACPICGKKFKVEWAYKTHMQRHEQERA 470
            ..|.|:||      |.|:.....:|..|:   .|.|.  |...|...:.: .:|.|:     :..
Yeast   390 IKGAFKCPYNSTLINLDMEVYPHKSRSLY---FEPIN--CHQTGVFSRCD-TFKNHL-----KAL 443

  Fly   471 HFRCELCPKIFRLRAELKHHMAQRHDEHGFI-YECKRCQRTF-LTQQRLQRHQAVGC 525
            ||  |..||             .:.::.|.: .:||.|...| .....|.:|...||
Yeast   444 HF--EYPPK-------------TKKEDRGVVPGKCKHCGLQFPNVDVWLNKHVGKGC 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	11/78 (14%)
		zf-C2H2	416..438	CDD:278523	7/27 (26%)
		C2H2 Zn finger	418..438	CDD:275368	6/25 (24%)
		zf-C2H2	443..465	CDD:278523	4/21 (19%)
		C2H2 Zn finger	445..465	CDD:275368	4/19 (21%)
		C2H2 Zn finger	474..491	CDD:275368	3/16 (19%)
		C2H2 Zn finger	504..521	CDD:275368	5/17 (29%)
STP4	NP_010235.1	COG5048	14..442	CDD:227381	51/257 (20%)
		C2H2 Zn finger	279..296	CDD:275368	4/23 (17%)
		C2H2 Zn finger	306..326	CDD:275368	6/56 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100