DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and si:ch211-214e3.5

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_001339026.1	Gene:	si:ch211-214e3.5 / 798582	ZFINID:	ZDB-GENE-050208-19	Length:	1413	Species:	Danio rerio

Alignment Length:	482	Identity:	92/482 - (19%)
Similarity:	157/482 - (32%)	Gaps:	135/482 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EQRQNPQESAQNQEQPQPRQDLAGKSVGSADDGVSGTVGQIMDYLEDDAGATADQDAEMGEAEYL 78
            |....|..|:..:|:..|....|..|:....|                   ....|||:||:...
Zfish   608 ENNNEPTTSSVAEERQGPNSVKAKTSLCEVTD-------------------KKTCDAELGESSQF 653

  Fly    79 -----------------DGEMPQEDESETPQTEKANEGCQESSNKKDLQESAAKDDFSKEKSGE- 125
                             ..|:.....:||....|.::|..|..|.:| ..|..:::|....|.|
Zfish   654 CSNGFSNSQASNIVLENSTEVINNKATETDSKNKTSKGKTEYKNPRD-SLSEVENNFLNSPSQEV 717

  Fly   126 ----DGEKDTDKEKKATHLHEDNNDDAEKDGDEADAED--------------EDDVEKPEDED-G 171
                :..|||......:...|:::.:.|::..|.|..|              ||..|.|.:.| .
Zfish   718 FSFHNYSKDTSGSSPESMQPEEDSQELEEEECEEDFGDWSLTLPASPPLPAEEDSKEGPNESDLV 782

  Fly   172 TEEGDEAIEEDEDALDEDEDPNEEVEEIEPDFETGTDAEGELITGDEPGDLADVPIRERKKEEP- 235
            :|.|::.:|...|:            :||.|....|..:..:....|.|..|.....|:|.|.|
Zfish   783 SESGEKTLERVSDS------------DIEVDECIATVDDSLIPVLPEKGGEATSLSTEKKPEGPA 835

  Fly   236 -VDEDQCRVCTSKEELVCLFKKQIDATPADMLLVICPNVSILPKDFMPQFICTKCMGSLTIAIQL 299
             .:|:......:...|..:.:|..||..:..          |.|:.|        |.|..:...:
Zfish   836 VANENTAPSLNNAAVLGKILEKHSDAIISQQ----------LEKERM--------MSSAPVQETV 882

  Fly   300 R--------------KQ---LETTDQELRKRLSRSKNKVRRPRGYVVID---APVTDSSEDEDEL 344
            |              ||   |:|||......:     :::...|:.:|.   :|..:.|..:..:
Zfish   883 RPTKTTLRILQTPEGKQQMFLQTTDTPYPVPV-----QLKSGAGFKLITKACSPKINVSYVKPGI 942

  Fly   345 DDEFKVSDVA--------GTTSADSDSADSDDSEKEKKKPGPRGRPRKKPLKRG-------TDSD 394
            :...|...||        |.::..|...:..::..:..:.|.|.......||..       ..|.
Zfish   943 ETACKTKGVALTLNGGRIGLSAQSSGLENKGEASVQTAQSGNRYFVNASALKASILLSGAVKSSS 1007

  Fly   395 GEPSSAQK------KKYQPSSTASVGP 415
            |||::...      ::..|.|:.|.||
Zfish  1008 GEPAANVPQTCYLVQRPLPVSSESTGP 1034

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	16/89 (18%)
		zf-C2H2	416..438	CDD:278523	92/482 (19%)
		C2H2 Zn finger	418..438	CDD:275368
		zf-C2H2	443..465	CDD:278523
		C2H2 Zn finger	445..465	CDD:275368
		C2H2 Zn finger	474..491	CDD:275368
		C2H2 Zn finger	504..521	CDD:275368
si:ch211-214e3.5	XP_001339026.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930