DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12391 and ZNF131

DIOPT Version :9

Sequence 1:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001284477.1 Gene:ZNF131 / 7690 HGNCID:12915 Length:623 Species:Homo sapiens


Alignment Length:302 Identity:65/302 - (21%)
Similarity:103/302 - (34%) Gaps:63/302 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   301 KQLETTDQELRKRLSRS--------KNKVRRPRGYVVIDAPVTDS---------SEDEDELDDE- 347
            |.||..::|....|..:        |.|:......:....|..:|         :|...|::|| 
Human   119 KALEVRNKENSAPLEENTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDEG 183

  Fly   348 ----FKVSDVAGTTSADSDSADSDDSE-------KEKKKPGPRGRPRKKPLKRGTDSDGEPSSAQ 401
                .:|:....:......:..||||.       ..|.:.|    .||..:|    .||.||...
Human   184 IETLEEVASAKQSVKYIQSTGSSDDSALALLADITSKYRQG----DRKGQIK----EDGCPSDPT 240

  Fly   402 KKKYQPSSTASV------GPFECPNCDLTFSRKQSYVLHRKTHERIEHACPICGKKFKVEWAYKT 460
            .|:.:......:      ..|.|..|:.:|.....:..|.|:|......|.||.|::..|.|:|.
Human   241 SKQVEGIEIVELQLSHVKDLFHCEKCNRSFKLFYHFKEHMKSHSTESFKCEICNKRYLRESAWKQ 305

  Fly   461 HMQRHEQE------------RAHFRCELCPKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLT 513
            |:..:..|            :.|. |:.|.|.|......|.|:.:...|..|  ||..|...|..
Human   306 HLNCYHLEEGGVSKKQRTGKKIHV-CQYCEKQFDHFGHFKEHLRKHTGEKPF--ECPNCHERFAR 367

  Fly   514 QQRLQRH-----QAVGCQRHKEDSVRIKEEQSRFKQESRSKD 550
            ...|:.|     ..||.::.::.....:...|.|....:.||
Human   368 NSTLKCHLTACQTGVGAKKGRKKLYECQVCNSVFNSWDQFKD 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12391NP_610639.1 zf-AD 240..313 CDD:285071 4/11 (36%)
zf-C2H2 416..438 CDD:278523 6/21 (29%)
C2H2 Zn finger 418..438 CDD:275368 5/19 (26%)
zf-C2H2 443..465 CDD:278523 8/21 (38%)
C2H2 Zn finger 445..465 CDD:275368 8/19 (42%)
C2H2 Zn finger 474..491 CDD:275368 5/16 (31%)
C2H2 Zn finger 504..521 CDD:275368 5/21 (24%)
ZNF131NP_001284477.1 BTB 24..122 CDD:279045 1/2 (50%)
BTB 35..122 CDD:197585 1/2 (50%)
Nuclear localization signal 1. /evidence=ECO:0000269|PubMed:17306895 137..148 2/10 (20%)
COG5048 <262..444 CDD:227381 36/151 (24%)
C2H2 Zn finger 263..283 CDD:275368 5/19 (26%)
C2H2 Zn finger 290..311 CDD:275368 8/20 (40%)
Nuclear localization signal 2. /evidence=ECO:0000269|PubMed:17306895 317..328 0/10 (0%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
zf-H2C2_2 342..367 CDD:290200 8/26 (31%)
C2H2 Zn finger 358..375 CDD:275368 4/16 (25%)
C2H2 Zn finger 394..414 CDD:275368 4/16 (25%)
C2H2 Zn finger 422..439 CDD:275370
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 573..623
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156920
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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