DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and Zfp518a

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_082595.1	Gene:	Zfp518a / 72672	MGIID:	1919922	Length:	1478	Species:	Mus musculus

Alignment Length:	214	Identity:	48/214 - (22%)
Similarity:	72/214 - (33%)	Gaps:	46/214 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 PSSAQKKKYQPSSTASVGPFECPNCDLTFSRKQSYVLHRKTHERIEHACPICGKKFKVEWAY--- 458
            |:..| |.::......:..|.|..|..:.|..|.:..|||||......|.||..    |.:|
Mouse   134 PNDLQ-KHFEMWHHGELPSFPCEMCSFSASDFQIFKQHRKTHRNTFVKCDICNS----ERSYTLL 193

  Fly   459 --KTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQ 521
              ..|.........:|:||.|....:.......|:.:..:.|   |:|.:|.....|:..||:|.
Mouse   194 DLTKHFTSKHCVNGNFQCEECRFFTQDVGTFVQHIHRHKEVH---YKCGKCHHLCFTKGELQKHL 255

  Fly   522 AVG----------CQR---HKEDSVR-----------IKEEQSRFKQESRSKDDRHHGNNSSKRR 562
            .|.          |..   ||:..:|           .||:..|.:.:.|.......|.....:|
Mouse   256 RVHSGTLPFTCHYCSYGAIHKDQLIRHVITLHKEHLYAKEKLERDQYDKRVAKTTTTGLKLILKR 320

  Fly   563 PGEGRDLFKAVAPPTTTYW 581
            ...|         ||.|:|
Mouse   321 YKIG---------PTKTFW 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071
		zf-C2H2	416..438	CDD:278523	8/21 (38%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		zf-C2H2	443..465	CDD:278523	6/26 (23%)
		C2H2 Zn finger	445..465	CDD:275368	6/24 (25%)
		C2H2 Zn finger	474..491	CDD:275368	3/16 (19%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)
Zfp518a	NP_082595.1	C2H2 Zn finger	181..203	CDD:275368	6/25 (24%)
		C2H2 Zn finger	211..231	CDD:275368	4/19 (21%)
		C2H2 Zn finger	238..258	CDD:275368	6/19 (32%)
		C2H2 Zn finger	266..283	CDD:275368	4/16 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	356..393
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	569..603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	658..696
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1282..1305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930