DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and plag1

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001034903.1	Gene:	plag1 / 561450	ZFINID:	ZDB-GENE-060302-2	Length:	393	Species:	Danio rerio

Alignment Length:	162	Identity:	43/162 - (26%)
Similarity:	70/162 - (43%)	Gaps:	18/162 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   416 FECPNCDLTFSRKQSYVLHRKTH--ERIEHACPI-CGKKFKVEWAYKTHMQRHEQERAHFRCELC 477
            |.|..|:..|:..:...:|..:|  ||..|.... |.|.|..::....||..|..|:.| :|..|
Zfish    31 FSCQLCEKAFNSLEKLKVHSYSHTGERPYHCTHTDCTKAFVSKYKLLRHMATHSPEKTH-KCSYC 94

  Fly   478 PKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQA--------VGCQ--RHKEDS 532
            .|:|..:..||:|: ..||.:...:.|..|.:::.|:...:||||        :.||  .....|
Zfish    95 EKMFHRKDHLKNHL-HTHDPNKEAFSCTECDKSYNTKLGFRRHQALHAAQRGDLTCQVCLQSYPS 158

  Fly   533 VRIKEEQSR---FKQESRSKDDRHHGNNSSKR 561
            ..:..|..|   .|..:.:|:.||..:...:|
Zfish   159 TPLLLEHLRGHAGKSATATKEKRHQCDQCERR 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071
		zf-C2H2	416..438	CDD:278523	5/21 (24%)
		C2H2 Zn finger	418..438	CDD:275368	4/19 (21%)
		zf-C2H2	443..465	CDD:278523	6/22 (27%)
		C2H2 Zn finger	445..465	CDD:275368	5/20 (25%)
		C2H2 Zn finger	474..491	CDD:275368	6/16 (38%)
		C2H2 Zn finger	504..521	CDD:275368	4/16 (25%)
plag1	NP_001034903.1	COG5048	29..>99	CDD:227381	20/68 (29%)
		C2H2 Zn finger	33..53	CDD:275368	4/19 (21%)
		C2H2 Zn finger	61..83	CDD:275368	5/21 (24%)
		zf-H2C2_2	76..100	CDD:290200	9/24 (38%)
		C2H2 Zn finger	91..111	CDD:275368	7/20 (35%)
		C2H2 Zn finger	120..140	CDD:275368	7/19 (37%)
		C2H2 Zn finger	149..169	CDD:275368	5/19 (26%)
		C2H2 Zn finger	184..204	CDD:275368	1/7 (14%)
		C2H2 Zn finger	212..230	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930