DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12391 and ZNF701

DIOPT Version :9

Sequence 1:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001166126.1 Gene:ZNF701 / 55762 HGNCID:25597 Length:531 Species:Homo sapiens


Alignment Length:203 Identity:48/203 - (23%)
Similarity:76/203 - (37%) Gaps:50/203 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   402 KKKYQPSSTASVG--PFECPNCDLTFSRKQSYVLHRKTH--ERIEHACPICGKKFKVE------- 455
            :|:|........|  |:.|..|..|||...:.::|:..|  |: .:.|..|||.|..:       
Human   320 QKRYLACHRCHTGENPYTCNECGKTFSHNSALLVHKAIHTGEK-PYKCNECGKVFNQQSNLARHH 383

  Fly   456 -----------------WAYKTHMQRHEQERAH-----FRCELCPKIFRLRAELKHHMAQRHDEH 498
                             ::.|:|::||  .|.|     ::|::|.|.||..:.|..|......|.
Human   384 RVHTGEKPYKCEECDKVFSRKSHLERH--RRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEK 446

  Fly   499 GFIYECKRCQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEEQSRFKQESRSKDDRHHGNNSSKRRP 563
            .  |:|..|.:||:....|..|:.            |...:.|:|.....|...|..|.:..||.
Human   447 P--YKCNECGKTFVQNSSLVMHKV------------IHTGEKRYKCNECGKVFNHKSNLACHRRL 497

  Fly   564 GEGRDLFK 571
            ..|...:|
Human   498 HTGEKPYK 505

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12391NP_610639.1 zf-AD 240..313 CDD:285071
zf-C2H2 416..438 CDD:278523 6/21 (29%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
zf-C2H2 443..465 CDD:278523 7/45 (16%)
C2H2 Zn finger 445..465 CDD:275368 7/43 (16%)
C2H2 Zn finger 474..491 CDD:275368 6/16 (38%)
C2H2 Zn finger 504..521 CDD:275368 5/16 (31%)
ZNF701NP_001166126.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..42
KRAB 74..>114 CDD:214630
KRAB 74..113 CDD:279668
C2H2 Zn finger 283..303 CDD:275368
zf-H2C2_2 296..320 CDD:290200 48/203 (24%)
C2H2 Zn finger 311..330 CDD:275368 2/9 (22%)
C2H2 Zn finger 338..358 CDD:275368 6/19 (32%)
zf-H2C2_2 350..375 CDD:290200 8/25 (32%)
C2H2 Zn finger 366..386 CDD:275368 5/19 (26%)
zf-H2C2_2 378..403 CDD:290200 0/24 (0%)
COG5048 <390..527 CDD:227381 31/132 (23%)
C2H2 Zn finger 394..414 CDD:275368 5/21 (24%)
zf-H2C2_2 406..431 CDD:290200 9/26 (35%)
C2H2 Zn finger 422..442 CDD:275368 7/19 (37%)
zf-H2C2_2 434..459 CDD:290200 8/26 (31%)
C2H2 Zn finger 450..470 CDD:275368 6/31 (19%)
zf-H2C2_2 462..487 CDD:290200 6/36 (17%)
C2H2 Zn finger 478..498 CDD:275368 5/19 (26%)
zf-H2C2_2 490..515 CDD:290200 5/16 (31%)
C2H2 Zn finger 506..526 CDD:275368 48/203 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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