DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and Zfp518b

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_008768453.1	Gene:	Zfp518b / 498390	RGDID:	1564150	Length:	1077	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	41/219 - (18%)
Similarity:	81/219 - (36%)	Gaps:	52/219 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 KKPGPRGRPRKKP----LKRGTDSDGE----PSSAQKKKYQ--PSSTASVGP------FECPNCD 422
            |:|....||.::.    |.:|::::..    .:..|.|...  |:.....||      :.|..|.
  Rat    30 KQPNRATRPERQEAQTLLYQGSEAEAATMTIATCVQCKSIHKIPTQDLRKGPGQGQDTYVCFKCS 94

  Fly   423 LTFSRKQSYVLHRK---THERIE--------------------HACPICGKKFKVEWAYKTHMQR 464
            |.....|.:.::..   .|.|.|                    :.|..|....|....|:.|..:
  Rat    95 LRAVPTQLHFVNNNAGAAHIRNETETISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQ 159

  Fly   465 HEQERAHFRCELCPKIFRLRAELKHHMAQRHDEHG--FIYECKRC-----QRTFLTQQRLQRHQA 522
            ||:.:  |.|..|..|...:.|.:.|:.    :|.  |.|.|:.|     :..::.:.|.:.|:.
  Rat   160 HEEIK--FICSHCSYISYTKGEFQRHLV----KHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHER 218

  Fly   523 VGCQRHKEDSVRIKEEQSRFKQES 546
            .|.:|..:...:::.:::...::|
  Rat   219 AGAKRPFKTVAKLEPKRTNISKQS 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071
		zf-C2H2	416..438	CDD:278523	4/24 (17%)
		C2H2 Zn finger	418..438	CDD:275368	4/22 (18%)
		zf-C2H2	443..465	CDD:278523	5/21 (24%)
		C2H2 Zn finger	445..465	CDD:275368	5/19 (26%)
		C2H2 Zn finger	474..491	CDD:275368	4/16 (25%)
		C2H2 Zn finger	504..521	CDD:275368	3/21 (14%)
Zfp518b	XP_008768453.1	C2H2 Zn finger	140..160	CDD:275368	5/19 (26%)
		C2H2 Zn finger	167..187	CDD:275368	5/23 (22%)
		zf-H2C2_2	179..200	CDD:290200	7/24 (29%)
		C2H2 Zn finger	195..216	CDD:275368	3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930