Protein Alignment CG12391 and LOC4576427

DIOPT Version :10

• Sequence 1: NP_610639.1
• Gene: CG12391 / 36170
• FlyBaseID: FBgn0033581
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_001688568.2
• Gene: LOC4576427 / 4576427
• VectorBaseID: AGAMI1_007464
• Length: 519
• Species: Anopheles gambiae
• Alignment Length: 556
• Identity: 169/556 - (30%)
• Similarity: 264/556 - (47%)
• Gaps: 110/556 - (19%)

  Fly    85 EDESETPQTEKANEGCQESSN---KKD-LQESAAKDDFSKEKSGEDGEKDTDK--------EKKA 137
            |:...|....|.:....||..   |.| |.::..|:|||:|...|:.|:..|:        |:..
Mosquito    21 ENSDSTANANKEDSAHAESEREVIKVDKLHDAEGKEDFSEEVEHEEEEETLDQSQGDAVETEEII 85

  Fly   138 THLHEDNNDDAEK-DGDEADAEDEDDVEKPED-EDGTEEGDEAIEEDEDALDEDEDPNE---EVE 197
            |...|...:|||. :.||.|..:||:||..|: :|.|......:::....|.:.||..:   |:.
Mosquito    86 TETLEKGAEDAEHLEEDEGDQVEEDNVEPLEEVDDATGAKPSKVKQTHQELSDAEDDKKITIEIL 150

  Fly   198 EIEPDFETGTDAEGELITGDEPGDLADVPIRERKKEEPVDEDQCRVCTSKEELVCLFKKQIDATP 262
            :.||..:..|.|.                 ..|:::..:..|.||||...|||..:|:.......
Mosquito   151 KSEPKEKLDTTAN-----------------VSREEKSTIALDMCRVCMGTEELSDIFQFDGPVRV 198

  Fly   263 ADMLLVICPNVSILPKDFMPQFICTKCMGSLTIAIQLRKQLETTDQELRKRLSRSKNKVRRPRGY 327
            :|:::.:|.|:.|..:|.:|..||.:|:|.:.|..:.:.:.|.:|:||||.|.||.||.||....
Mosquito   199 SDIIMKVCTNIRITARDHLPHKICEQCLGQVRIVNEFKNRCEASDKELRKNLKRSTNKSRRQSEV 263

  Fly   328 VVIDAPVTDSSEDEDEL--DDEFKVSDVAGTTSADSDSADSDDS----EKEKK-------KPGPR 379
            :|::.|::||.:|::|.  |||:|||.    :..:|:.|.||||    .|.|:       :|..|
Mosquito   264 IVVNCPMSDSDKDDEEPVDDDEYKVSQ----SEVESEPATSDDSFSPPNKRKRTPKRRVGRPPGR 324

  Fly   380 GRPRKKP-----------LKRGTDSDGEPSSAQKKKY-QPSSTASVGPFECPNCDLTFSRKQSYV 432
            |||.:||           :|||   .|.|     .|| :.||..::...|.|. |.:.|.:::.|
Mosquito   325 GRPGRKPKNMVVSTPKFAVKRG---PGRP-----PKYPKTSSLTNIVYIEAPE-DSSSSGEEAEV 380

  Fly   433 LHRKTHERIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRHDE 497
            . .|..:|.::.||.|.:....:.|.|.|::.|..:|  |.|:.|...||....|.:|: :||.:
Mosquito   381 T-PKRRKRGDNPCPKCDEVLPSQLALKQHLKTHPGDR--FDCDRCALFFRTEKALSNHI-ERHKK 441

  Fly   498 HGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEEQSRFKQES----RSKDDRHHGN-N 557
            ...|.|.||.:|    :||:                   |::||:..:|    :||.....|: .
Mosquito   442 ADKIREEKRKER----EQRI-------------------EQRSRYTPKSSDAEKSKLISPQGSAT 483

  Fly   558 SSKRRPGE------GRDLFKAVAPPTTTYWSDSFSD 587
            :.|::..|      ||||||.|||.|:|||||||||
Mosquito   484 AEKKKKSEPSAASSGRDLFKCVAPLTSTYWSDSFSD 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	2A1904	<9..240	CDD:273344	41/171 (24%)
		zf-AD	240..312	CDD:214871	23/71 (32%)
		PRK05580	<416..>449	CDD:455857	9/32 (28%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-C2H2	443..465	CDD:395048	6/21 (29%)
		C2H2 Zn finger	445..465	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..491	CDD:275368	5/16 (31%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)
LOC4576427	XP_001688568.2	None