DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and Zfp174

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001074686.1	Gene:	Zfp174 / 385674	MGIID:	2686600	Length:	407	Species:	Mus musculus

Alignment Length:	403	Identity:	86/403 - (21%)
Similarity:	129/403 - (32%)	Gaps:	149/403 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 KEELVCL-------------FKKQI-DATPADMLLVICP----------------NVSILPKDF- 280
            :|.|.||             .|:|| :....:..|||.|                .:..|.:|.
Mouse    61 QEALSCLQQLCRQWLQPELHTKEQILELLVMEQFLVILPPEIQAQVWHRYPKSSREIVTLVEDLH 125

  Fly   281 ----MPQFICTKCMGSLTIAIQLRKQLETTDQELRKRLSRSKNKVRRPRGYVVIDAPVTDSSE-D 340
                .|:...|.||....:.:: :...:..:||||.                  ..|.|.|.: .
Mouse   126 RTSKKPKQWVTVCMQGQKVLLE-KTGAQLVEQELRD------------------FQPQTPSRDIQ 171

  Fly   341 EDELDD---------------EFKV--SDVAGTTSADSDSADSD-DSEKEKKKPGPR------GR 381
            ||.|::               |..|  ..|...|..:|.....| ::.|:::..|.:      ||
Mouse   172 EDSLEEPSCEGSHEQLSPHHWEKTVLQEPVLRLTETESSRMRGDKENPKQEEARGAKACTVLHGR 236

  Fly   382 PRKKPLKRGTDSDGEP-----SSAQKKKYQ---PSSTASVGPFE--C-------------PNCDL 423
            |     |.||....||     |.|:..::|   |.|..|:..::  |             |..:|
Mouse   237 P-----KGGTLHSPEPRGVTASDARLLQWQVRPPQSPKSLAHYQKHCRELEYISNPLRGHPLREL 296

  Fly   424 TFS-----RKQSYVL----HRKTH-ERIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELCP 478
            ..|     |..|.:|    |:..| .:..::|..|||.|......|.|.:.|..||.:. |..|.
Mouse   297 KRSRGGRRRSLSGLLQCLGHQAAHPAKKPYSCEDCGKNFTWNSELKRHRRVHTGERPYI-CGECG 360

  Fly   479 KIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEEQSRFK 543
            ..|..::.||.|  ||.......|:|..|.:.|.....|.:|..:
Mouse   361 NCFGRQSTLKLH--QRIHTGEKPYQCSHCGKCFRQSSNLHQHHRL-------------------- 403

  Fly   544 QESRSKDDRHHGN 556
                     ||||
Mouse   404 ---------HHGN 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	21/100 (21%)
		zf-C2H2	416..438	CDD:278523	8/45 (18%)
		C2H2 Zn finger	418..438	CDD:275368	8/41 (20%)
		zf-C2H2	443..465	CDD:278523	7/21 (33%)
		C2H2 Zn finger	445..465	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..491	CDD:275368	5/16 (31%)
		C2H2 Zn finger	504..521	CDD:275368	4/16 (25%)
Zfp174	NP_001074686.1	SCAN	42..152	CDD:128708	17/91 (19%)
		SCAN	42..130	CDD:280241	13/68 (19%)
		C2H2 Zn finger	328..348	CDD:275368	7/19 (37%)
		zf-H2C2_2	340..365	CDD:290200	8/25 (32%)
		COG5048	352..>407	CDD:227381	17/86 (20%)
		C2H2 Zn finger	356..376	CDD:275368	8/21 (38%)
		zf-H2C2_2	369..393	CDD:290200	9/25 (36%)
		C2H2 Zn finger	384..404	CDD:275368	5/48 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930