DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12391 and ZSCAN5B

DIOPT Version :9

Sequence 1:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001073925.2 Gene:ZSCAN5B / 342933 HGNCID:34246 Length:495 Species:Homo sapiens


Alignment Length:555 Identity:108/555 - (19%)
Similarity:181/555 - (32%) Gaps:184/555 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEADITPLAETNGEQR-QNPQESAQNQEQPQPRQ--DLAGKSVGSADDGVSGTVGQIMDYLEDDA 62
            |..::..|.:.||.|. ::.::..:|..:|:...  :|.||                 :||    
Human    96 MPQELQVLVKVNGVQSCKDLEDLLRNNRRPKKWSIVNLLGK-----------------EYL---- 139

  Fly    63 GATADQDAEMGEAEYLDGEMPQEDESE-TPQTEKANEGCQESSNKKDLQESAAKDDFSKEKSGED 126
              ..:.|.||.||.....:.|::..|: .....:.:.|..::..::.:....|.   ...:.|||
Human   140 --MLNSDVEMAEAPASVRDDPRDVSSQWASSVNQMHPGTGQARREQQILPRVAA---LSRRQGED 199

  Fly   127 GEKDTDKEKKATHLHEDNNDDAEKDGDEADAEDEDDVEKPEDEDGTEEGDEAIEEDEDALDEDED 191
                       ..||:           ..|...:.:..:|:         :.:|:|   |.|:.:
Human   200 -----------FLLHK-----------SIDVTGDPNSPRPK---------QTLEKD---LKENRE 230

  Fly   192 PNEEVEEIEPDFETGTDAEGELI---TGDEPGDLADVPIRERKKEEPVDEDQCRVCTSKEELVCL 253
            .|..:...||......:    |:   .|.||        ::|...|.||.|....|..:.|.:..
Human   231 ENPGLSSPEPQLPKSPN----LVRAKEGKEP--------QKRASVENVDADTPSACVVEREALTH 283

  Fly   254 FKKQIDATPADMLLVICPNVSILPKDFMPQFICTKCMGSLTIAIQLRKQLETTDQELRKRLSRSK 318
            ...:.||.          |:| .||                                     |||
Human   284 SGNRGDAL----------NLS-SPK-------------------------------------RSK 300

  Fly   319 NKVRRPRGYVVIDAPVTDSSEDEDELDDEFKVSDVAGTTSADSDSADSDDSEKEKKKPGPRGRPR 383
                          |...|...|:...:...|.:......|:.:...|         |||.| |.
Human   301 --------------PDASSISQEEPQGEATPVGNRESPGQAEINPVHS---------PGPAG-PV 341

  Fly   384 KKPLKRGTDSDGEPSSAQ--------KKKYQPSSTASV--------GPFECPNCDLTFSRKQSYV 432
            ..|       ||:.:.|.        .|.::..|..|:        .||:|..|...|.:.....
Human   342 SHP-------DGQEAKALPPFACDVCNKSFKYFSQLSIHRRSHTGDRPFQCDLCRKRFLQPSDLR 399

  Fly   433 LHRKTH--ERIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRH 495
            :|::.|  || .:.|.:|.|:|..|...:.|.:.|..||. |:|:.|.|:|..:..|..|.....
Human   400 VHQRVHTGER-PYMCDVCQKRFAHESTLQGHKRIHTGERP-FKCKYCSKVFSHKGNLNVHQRTHS 462

  Fly   496 DEHGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKE 530
            .|..  |:|..||:.|......:||    .:.|:|
Human   463 GEKP--YKCPTCQKAFRQLGTFKRH----LKTHRE 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12391NP_610639.1 zf-AD 240..313 CDD:285071 8/72 (11%)
zf-C2H2 416..438 CDD:278523 5/21 (24%)
C2H2 Zn finger 418..438 CDD:275368 4/19 (21%)
zf-C2H2 443..465 CDD:278523 6/21 (29%)
C2H2 Zn finger 445..465 CDD:275368 6/19 (32%)
C2H2 Zn finger 474..491 CDD:275368 5/16 (31%)
C2H2 Zn finger 504..521 CDD:275368 5/16 (31%)
ZSCAN5BNP_001073925.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
SCAN 40..124 CDD:153421 6/27 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..183 4/32 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 227..347 37/210 (18%)
zf-C2H2 355..377 CDD:395048 3/21 (14%)
C2H2 Zn finger 357..377 CDD:275368 3/19 (16%)
zf-H2C2_2 370..394 CDD:404364 6/23 (26%)
C2H2 Zn finger 385..405 CDD:275368 4/19 (21%)
C2H2 Zn finger 413..433 CDD:275368 6/19 (32%)
zf-H2C2_2 426..450 CDD:404364 9/24 (38%)
C2H2 Zn finger 441..461 CDD:275368 6/19 (32%)
zf-H2C2_2 453..478 CDD:404364 8/26 (31%)
C2H2 Zn finger 469..489 CDD:275368 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156908
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.