DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and CG15436

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	83/346 - (23%)
Similarity:	138/346 - (39%)	Gaps:	53/346 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 CRVCTS-KEELVCLF--KKQIDATPADMLLVICPNVSILPKDFMPQFICTKCMGSLTIAIQLRKQ 302
            ||||.. ..:||.:|  :::...:.|:| :..|....:...|...:.||.:|...:..|..:|:
  Fly     5 CRVCMDISGKLVNIFDARRRTRVSIAEM-IAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQ- 67

  Fly   303 LETTDQELRKRLSRSKNKVRRPRGYVVIDAPVTDSSEDEDELDDEFKVSDVAGTTSADSDSADSD 367
               |.:|..:...|.:::........:::....:.|||||              ...||.||..|
  Fly    68 ---TCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDED--------------ARIDSASAADD 115

  Fly   368 DSEKEKKKPGPRGRP-RKKPLKRGT---------DSDGEPSSAQKKKYQPSSTA--------SVG 414
            |.:.:.||.....|. .||..::||         |....|....|:.::...|.        :..
  Fly   116 DGKSDSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAK 180

  Fly   415 PFECPNCDLTFSRKQSYVLHRKTH--ERIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELC 477
            |:||.:|..||:::.:...|.:||  || ...|..|.|.|......:.|::.|..||. |:|..|
  Fly   181 PYECSHCAKTFAQQSTLQSHERTHTGER-PFKCSQCSKTFIKSSDLRRHIRTHGSERP-FKCSKC 243

  Fly   478 PKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKED-SVRIKEEQSR 541
            .|.|..:..|.:|......|..|  :|..|.:.|..:|.|::|..:    |..| ..|.......
  Fly   244 TKTFTRKFHLDNHFRSHTGERPF--KCSHCPKAFAMKQHLKQHSRL----HLPDRPFRCSHCPKT 302

  Fly   542 FKQESRSKDDR--HHGNNSSK 560
            |:..|..|:.:  |:...:.|
  Fly   303 FRLSSTLKEHKLVHNAERTFK 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	18/74 (24%)
		zf-C2H2	416..438	CDD:278523	6/21 (29%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-C2H2	443..465	CDD:278523	5/21 (24%)
		C2H2 Zn finger	445..465	CDD:275368	5/19 (26%)
		C2H2 Zn finger	474..491	CDD:275368	5/16 (31%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	18/77 (23%)
		C2H2 Zn finger	128..148	CDD:275368	5/19 (26%)
		C2H2 Zn finger	156..176	CDD:275368	2/19 (11%)
		COG5048	<180..341	CDD:227381	42/152 (28%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		zf-H2C2_2	197..219	CDD:290200	8/22 (36%)
		C2H2 Zn finger	212..232	CDD:275368	5/19 (26%)
		zf-H2C2_2	224..249	CDD:290200	9/25 (36%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	252..276	CDD:290200	6/25 (24%)
		C2H2 Zn finger	268..288	CDD:275368	6/23 (26%)
		C2H2 Zn finger	296..316	CDD:275368	3/19 (16%)
		C2H2 Zn finger	324..341	CDD:275368	83/346 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010