Protein Alignment CG12391 and Zfp496

DIOPT Version :10

• Sequence 1: NP_610639.1
• Gene: CG12391 / 36170
• FlyBaseID: FBgn0033581
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006246512.1
• Gene: Zfp496 / 287361
• RGDID: 1304611
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 109/517 - (21%)
• Similarity: 184/517 - (35%)
• Gaps: 167/517 - (32%)

  Fly   164 EKPEDEDGTEEGDEAIE-------------EDEDALDEDEDP---NEEVEEIEPDFETGTDA-EG 211
            ::||..:......||:|             ||...:|:.:.|   :.|.|.:..:.::..|| .|
  Rat   105 QEPESGEQAVAAVEALEREPGRPWQWLKHCEDPVVIDDGDGPAPQDLEQERMSAESQSNPDALPG 169

  Fly   212 ELITGDEPGDLADVPIRERKKEEPVDED----------------QC-----RVCTSKEELVCLFK 255
            .|  ..:||.|:..|  .:..|:||.:|                .|     ||...|:.::|..:
  Rat   170 AL--AQDPGLLSRSP--GQPSEDPVPQDAVLSQEQSVRDAQPVTTCQLPPNRVSPFKDMILCFSE 230

  Fly   256 KQ---IDATPA------------DMLLVICPNVS---------------------ILPKDFMPQF 284
            :.   :|  ||            |..:.:.||.|                     :..|: .||.
  Rat   231 EDWSLLD--PAQTGFYGEFIIGEDYAVSMPPNESPVQLGHSHEEENGLRVTEWTDLQDKE-APQA 292

  Fly   285 ICTKCMGSLTIAIQLRKQLETTDQELRKRLSRSKNKVRRPRGYVVIDAPVT------DSSEDEDE 343
            .|.              .|:....|.||:.  .:.:|..|:....:..|.:      |....::.
  Rat   293 SCI--------------DLQPFQGEERKKW--EELQVPEPQSCQQVVLPPSPCPAGGDPPPLKNN 341

  Fly   344 LDDEFKVSDVAGTTSADSDSADSDDSEKEKKKPGPRGRPRKKPLKRGTDSDGEPSSAQKKKYQPS 408
            ||.|..: ::..::|.|.||..|....:|.:.| |.........:..|...||..|:||.
  Rat   342 LDQEVTI-EIVLSSSGDEDSQHSPYCTEELRSP-PENLHSLPAPQSNTRPGGEVQSSQKS----- 399

  Fly   409 STASVGPFECPNCDLTFSRKQSYVLH-RKTHERIEHACPICGKKFKVEWAYKTHMQRHEQERAHF 472
                   :.||:|...|..:.:::.| |...|:..|.|.:||:.|........|::.||.::. :
  Rat   400 -------YVCPSCGKAFRWRVNFIRHLRSRREQKPHKCSVCGELFSDSEDLDGHLETHEAQKP-Y 456

  Fly   473 RCELCPKIFRLRAELKHHM-----------AQRHDEH--------------------GFIYECKR 506
            ||.:|.|.|||.:.|..|.           .::::|.                    ||  :|..
  Rat   457 RCTVCGKSFRLNSHLISHQRIHLQPDKQQPLKKNEEDSLETESTGTNDLLEKSKAKLGF--QCAD 519

  Fly   507 CQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEE----QSRF--KQESRSKDDRHHGNNSSKRR 562
            |:::|.....|.||     :||    ..:|:|    |.|:  |...::.|...|.....|||
  Rat   520 CEKSFQRHDYLVRH-----RRH----CHLKDETRPFQCRYCVKTFRQNYDLLRHERLHMKRR 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	2A1904	<9..240	CDD:273344	23/108 (21%)
		zf-AD	240..312	CDD:214871	18/112 (16%)
		PRK05580	<416..>449	CDD:455857	9/33 (27%)
		C2H2 Zn finger	418..438	CDD:275368	6/20 (30%)
		zf-C2H2	443..465	CDD:395048	6/21 (29%)
		C2H2 Zn finger	445..465	CDD:275368	5/19 (26%)
		C2H2 Zn finger	474..491	CDD:275368	7/16 (44%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)
Zfp496	XP_006246512.1	SCAN	50..126	CDD:460417	5/20 (25%)
		KRAB_A-box	220..>248	CDD:470626	5/29 (17%)
		COG5048	<332..568	CDD:227381	60/261 (23%)
		C2H2 Zn finger	402..422	CDD:275368	6/19 (32%)
		C2H2 Zn finger	430..450	CDD:275368	5/19 (26%)
		C2H2 Zn finger	458..478	CDD:275368	8/19 (42%)
		C2H2 Zn finger	517..538	CDD:275370	8/29 (28%)
		C2H2 Zn finger	548..568	CDD:275368	4/19 (21%)