DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12391 and Y5F2A.4

DIOPT Version :9

Sequence 1:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_502063.1	Gene:	Y5F2A.4 / 178004	WormBaseID:	WBGene00012385	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	189	Identity:	45/189 - (23%)
Similarity:	72/189 - (38%)	Gaps:	55/189 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   415 PFECPNCDLTFSRKQSYVLHRKTHERI-EHACPICGKKFKVEWAYKTHMQRHEQERAHFR----- 473
            |.:|..||..|.|......|:.||..: .::|..|.:||    ..|:|:.|| ..|.|..
Worm    42 PLKCSMCDKVFPRLSHLQRHQMTHLNVRNYSCTFCEEKF----VQKSHLTRH-VSRKHSNAPGVE 101

  Fly   474 -----CELCPKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTF-LTQQRLQRHQAVGCQRH---- 528
                 |:.|.::|:...|::.|....|:.|    :||:||... .....|::|. :.|:::
Worm   102 VDWTACDKCGQLFKTTYEMRIHRQTYHELH----KCKQCQEVIEAGSDGLRKHH-MQCRKYSNVC 161

  Fly   529 ---------------------KEDSVRIKEEQSRFKQESRSKDDRH------HGNNSSK 560
                                 |:.:...|...|.|:|  |.:.|||      |....||
Worm   162 DECGASFSRPADLVSHETSCLKKFAFVCKPCDSYFRQ--RVQLDRHIKKAHFHPTKCSK 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071
		zf-C2H2	416..438	CDD:278523	6/21 (29%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		zf-C2H2	443..465	CDD:278523	6/21 (29%)
		C2H2 Zn finger	445..465	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..491	CDD:275368	4/16 (25%)
		C2H2 Zn finger	504..521	CDD:275368	5/17 (29%)
Y5F2A.4	NP_502063.1	C2H2 Zn finger	6..27	CDD:275368
		zf-C2H2	44..65	CDD:278523	6/20 (30%)
		C2H2 Zn finger	45..65	CDD:275368	6/19 (32%)
		C2H2 Zn finger	73..94	CDD:275368	9/25 (36%)
		C2H2 Zn finger	107..126	CDD:275368	5/18 (28%)
		C2H2 Zn finger	161..181	CDD:275368	0/19 (0%)
		C2H2 Zn finger	189..212	CDD:275368	8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156313
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930