DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12391 and Zfp369

DIOPT Version :9

Sequence 1:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_848141.3 Gene:Zfp369 / 170936 MGIID:2176229 Length:845 Species:Mus musculus


Alignment Length:512 Identity:90/512 - (17%)
Similarity:155/512 - (30%) Gaps:186/512 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 DPNEE-----------VEEIEPDFETGTDAEGELITGDEPGDLADVPIRERKKEEPVDEDQCRVC 244
            |||.:           .|.|.||     :.:|.......|..|.......::|.....:.|.:.|
Mouse   364 DPNPKDLSRNRTQSTLFESISPD-----EVQGRHTIESNPVGLLQEKGHPQQKLSESSKSQNQTC 423

  Fly   245 TSKEELVCLFKKQIDATPADMLLVICPNVSILPKDFMPQFICTKCMG---------SLTIAIQLR 300
            ..|.:                    |....:||::.:.  :..|..|         |:|..:::|
Mouse   424 IDKSQ--------------------CSLNEVLPRNHVK--VKQKGTGKGKGRTNTISMTGGLRIR 466

  Fly   301 KQ----LETTDQE-----------LRKRLSRSKNKVRRPRGYVVIDAPVTDSSEDEDELDDEFKV 350
            .|    :|..|:.           ..::|...:.|.:..|..:.:..|.....|.....:..|:.
Mouse   467 NQQKDSVEWRDRSGSTPVTHGSSIKNQQLGSEQGKTQTSRDPITLAVPAEFYQEATGSEEGRFRN 531

  Fly   351 SDVAGTTSA---------------DSDSADSDDSEKEKKKPGPR-GRPRK--------------- 384
            |..|....|               .|:::....|..:..:.|.| ||.|.               
Mouse   532 SSNAMAADAPPKIHQKGPEWHKAGKSNNSMLQGSSAQNHQMGSRAGRARDNSILTHVKIHQKGYK 596

  Fly   385 --------------KPLKRGTDSD--GEPSSAQK-----KKYQPSS--------TASV--GPF-- 416
                          ||.::|:..:  .|.|:.||     |::..:|        .||:  ||:  
Mouse   597 EGKIQGNNNYLKHVKPHQKGSKEERLRELSTCQKHVPYVKQHLKTSGRGKGRKINASIKCGPYIK 661

  Fly   417 ----------------------------------------ECPNCDLTFSRKQSYVLHRKTH--E 439
                                                    :|..|...|...:.:.:|:|.|  |
Mouse   662 TYYRGSDVGRLRRANNCRKAISRHAQQISFIKIHKGSQICQCSECGKMFRNARYFSVHKKIHTGE 726

  Fly   440 RIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRHDEHGFIYEC 504
            | .:.|..|||.|....:...|::.|..||. |.|..|.:.|..|:....|:  |.......|:|
Mouse   727 R-PYMCMSCGKAFVQSSSLTQHLRIHSGERP-FECSECGRTFSDRSAASQHL--RTHTGAKPYQC 787

  Fly   505 KRCQRTFLTQQRLQRHQAV----------GCQRHKEDSVRI----KEEQSRFKQESR 547
            :.|.:.|.....|.||..:          .|.:....|..:    |..:.:||::.:
Mouse   788 QHCGKAFRQSSHLTRHVRIHTGERPYVCTKCGKAFTQSSNLIGHQKTHRKKFKKQPK 844

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12391NP_610639.1 zf-AD 240..313 CDD:285071 14/96 (15%)
zf-C2H2 416..438 CDD:278523 5/63 (8%)
C2H2 Zn finger 418..438 CDD:275368 5/19 (26%)
zf-C2H2 443..465 CDD:278523 6/21 (29%)
C2H2 Zn finger 445..465 CDD:275368 6/19 (32%)
C2H2 Zn finger 474..491 CDD:275368 4/16 (25%)
C2H2 Zn finger 504..521 CDD:275368 5/16 (31%)
Zfp369NP_848141.3 KRAB 35..94 CDD:214630
KRAB 35..74 CDD:279668
SCAN 179..266 CDD:280241
KRAB 300..>340 CDD:214630
KRAB 300..339 CDD:279668
C2H2 Zn finger 676..695 CDD:275370 0/18 (0%)
C2H2 Zn finger 703..723 CDD:275368 5/19 (26%)
zf-H2C2_2 715..740 CDD:290200 10/25 (40%)
COG5048 727..>792 CDD:227381 20/68 (29%)
C2H2 Zn finger 731..751 CDD:275368 6/19 (32%)
zf-H2C2_2 743..767 CDD:290200 7/24 (29%)
zf-C2H2 757..779 CDD:278523 7/23 (30%)
C2H2 Zn finger 759..779 CDD:275368 6/21 (29%)
zf-C2H2 785..807 CDD:278523 7/21 (33%)
C2H2 Zn finger 787..807 CDD:275368 6/19 (32%)
zf-H2C2_2 799..824 CDD:290200 4/24 (17%)
C2H2 Zn finger 815..835 CDD:275368 3/19 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167847326
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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