DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and GPR142

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_861455.1	Gene:	GPR142 / 350383	HGNCID:	20088	Length:	462	Species:	Homo sapiens

Alignment Length:	237	Identity:	50/237 - (21%)
Similarity:	90/237 - (37%)	Gaps:	63/237 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 SIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREAILLPFILSPILCLPTYFVFQVRETYDVDKVN 230
            |:.:.:.|.|.||.|:.||....|......:|.||......:.:..:|.|:...:....|..:..
Human   245 SVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTL 309

  Fly   231 SEAMYHVYFDKDSVLYRFNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKY 295
            .|.:.               |.|.:.:..:|||:.:|.::.::|.|    |||
Human   310 DEVLK---------------WAHCLTVYFIPCGVFLVTNSAIIHRL----RRR------------ 343

  Fly   296 AIQLNLNETKSKKPPRCDRRNDRTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCY-PPF 359
                    .:|...||.    .::|.:|:.:..||.:...|:..:.|.          |.| .|.
Human   344 --------GRSGLQPRV----GKSTAILLGITTLFTLLWAPRVFVMLY----------HMYVAPV 386

  Fly   360 G---------ELMDLLALINAAVGFVLYGLMSKQFRTTFRSL 392
            .         ::.:::|:::.|..|.||..:||.||.|.|.:
Human   387 HRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQV 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	50/237 (21%)
GPR142	NP_861455.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..123
GPR142	NP_861455.1	7tm_1	176..414	CDD:278431	42/221 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I4901
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.050