DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and Gpr139

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001019412.1	Gene:	Gpr139 / 293545	RGDID:	1311729	Length:	345	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	88/365 - (24%)
Similarity:	160/365 - (43%)	Gaps:	89/365 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 YVSLMICIFGTIANILNIMVLTR--KEMAKTPINNILKWLAVADMFVM--LEYIPYTSYQYI--- 135
            |.|.::|: |..||||.:::|::  ....|:..|.:|. ||.||:.|:  :.::.:....:|
  Rat    24 YYSFLLCL-GLPANILTVIILSQLVARRQKSSYNYLLA-LAAADILVLFFIVFVDFLLEDFILTM 86

  Fly   136 YMGP-GEKDLSYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREA 199
            .|.| .:|         ::..:.|:.| || ||.:||.|.|.||:|:.||.........|.:|:.
  Rat    87 QMPPIPDK---------IIEVLEFSSI-HT-SIWITVPLTVDRYIAVCHPLKYHTVSYPARTRKV 140

  Fly   200 ILLPFILSPILCLPTYFVFQV-RETYDVDKVNSEAMYHVYFDKDSVLYRFNFWIHSVLIKLLPCG 263
            ||..:|...:..:|.|:...: .|.|     .|.:|:||.           .|||...:.|:||.
  Rat   141 ILSVYITCFLTSIPYYWWPNIWTEDY-----ISTSMHHVL-----------VWIHCFTVYLVPCS 189

  Fly   264 ILIVISAVLMHVLCEASRRR--LKLRDYNNPAKYAIQLNLNETKSKKPPRCDRRNDRTTLLLVAV 326
            |..::::::::.|    ||:  .:||.|:                         ..:||.:|..:
  Rat   190 IFFILNSIIVYKL----RRKSNFRLRGYS-------------------------TGKTTAILFTI 225

  Fly   327 LVLFLITEFPQGLL---GLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFVLYGLMSKQFRT- 387
            ..:|.....|:.::   .|....::..:..|.   ..::.::|||:|.|:.|.||..:||:|||
  Rat   226 TSIFATLWAPRIIMILYHLYGAPIQNPWLVHI---MLDVANMLALLNTAINFFLYCFISKRFRTM 287

  Fly   388 ---TFRSLF----------MKRHFGSTEMTRLTRVTTTCV 414
               |.::||          ...:|..|....::...:.|:
  Rat   288 AAATLKALFKCQKQPVQFYTNHNFSITSSPWISPANSHCI 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	83/332 (25%)
Gpr139	NP_001019412.1	7tmA_GPR139	19..288	CDD:320585	82/324 (25%)
		TM helix 1	21..45	CDD:320585	9/21 (43%)
		TM helix 2	55..77	CDD:320585	7/22 (32%)
		TM helix 3	94..116	CDD:320585	10/32 (31%)
		TM helix 4	139..155	CDD:320585	3/15 (20%)
		TM helix 5	173..196	CDD:320585	9/33 (27%)
		TM helix 6	219..241	CDD:320585	4/21 (19%)
		TM helix 7	256..281	CDD:320585	9/27 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010