DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and dmsr-11

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_504725.2	Gene:	dmsr-11 / 191158	WormBaseID:	WBGene00022605	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	86/354 - (24%)
Similarity:	150/354 - (42%)	Gaps:	80/354 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LRAYNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADMFVMLEYIP----- 128
            ::||...|.||...|.||...||||.:::||||||..:.:|..:..:||.|:...:..:.
Worm    35 VKAYRPFHYYVLTFIVIFAFFANILILILLTRKEMRYSGVNVTMMLIAVCDLGCAIAGLSQLYLR 99

  Fly   129 -----YTSYQYIYMGPGEKDLSYTWAVCLLVHMHFTQI-LHTISIGLTVTLAVWRYVAIRHPNGG 187
                 |:|||..|               ....:::.|| .|..|:.|.|.:|..|.:.:..
Worm   100 NFSDNYSSYQTAY---------------AQFIVYYCQIAFHAESLYLAVGMAFCRVITLSS---- 145

  Fly   188 CANFLLAHSREAILLP---FILSPILCLPTY-------FVFQVRETYDVDKVNSEAMYHVYFD-- 240
                 .:.||:....|   ..::.:||.|.:       |:..|:|.|        |...|:.|
Worm   146 -----ASDSRDTWQSPKYAIRVAVLLCFPVFAVSSFVLFLNSVKEVY--------ADGSVFLDIS 197

  Fly   241 -----KDSVLYRFNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLN 300
                 .|.:..:.:.:......|:|| .||:.:.::::.:..:|.::|            :..|:
Worm   198 PLSLANDCLFLKTSIFFSGSCFKILP-SILMSMFSIIILIRIKAGKQR------------SNSLS 249

  Fly   301 LNETKSKKPPRCDRRNDRTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDL 365
            .|:|..      |.:.||:|..:..|:|:|:|||.|||...:|..:....:..: |......|::
Worm   250 HNQTDQ------DAQIDRSTRFIQVVVVVFVITETPQGFFSVLGSISINDYINY-YQHLSIFMNI 307

  Fly   366 LALINAAVGFVLYGLMSKQFRTTFRSLFM 394
            ||..|....|::|..:|.:||..|..||:
Worm   308 LAFFNTTTSFIIYSTLSSKFRKLFAQLFV 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	81/342 (24%)
dmsr-11	NP_504725.2	7tmA_FMRFamide_R-like	40..331	CDD:320109	81/342 (24%)
		TM helix 1	42..66	CDD:320109	11/23 (48%)
		TM helix 2	75..96	CDD:320109	4/20 (20%)
		TM helix 3	115..137	CDD:320109	6/21 (29%)
		TM helix 4	161..177	CDD:320109	3/15 (20%)
		TM helix 5	209..232	CDD:320109	5/23 (22%)
		TM helix 6	260..285	CDD:320109	12/24 (50%)
		TM helix 7	299..324	CDD:320109	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870