DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and dmsr-6

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_497004.1	Gene:	dmsr-6 / 190297	WormBaseID:	WBGene00013222	Length:	394	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	96/341 - (28%)
Similarity:	168/341 - (49%)	Gaps:	42/341 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 EIYNWLRAYNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADMFVMLEYIP 128
            :.|.:...|:::|.::|.::|:.|..||.::|.||||..|..:.::.:|..:|::||..|..|:.
Worm    22 QFYRFRYLYSNVHPFLSFILCVLGLAANAIHITVLTRPRMRHSSVHTVLVCIAISDMGTMTSYLM 86

  Fly   129 YTS-YQYIYMGPGEKDLSYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFL 192
            |.| ::::   ..::..||.||:.|..|...:..||.|::.|.|.:|..|..|::.    ..:..
Worm    87 YISRFEFL---SDKEGYSYFWALFLKCHAMLSIALHAITLYLVVLMAFIRLSAMKL----TTSRW 144

  Fly   193 LAHSR---EAILLPFILSPILCLPTYFVFQVRETYDVDKVNSEAMYHVY--------FDKDSVLY 246
            |.|:|   .||.:...:. |:|:||....|:.||  ...|....||:.|        ......|.
Worm   145 LDHTRALTSAIFIALFVF-IMCVPTLLAHQIDET--TRGVTMNGMYYKYSVGFSTLMMQNGCSLM 206

  Fly   247 RFNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKKPPR 311
            :.|.|:..:.:|.:||.:|:..:..|::          :||:.|...|..|          |..|
Worm   207 KGNLWLTGIFLKAIPCLLLLTFTIALIN----------RLRENNEKRKILI----------KEER 251

  Fly   312 CDRRNDRTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFV 376
            ..:|.|.||.:|:.::.:||.||.|||::.:|:.:....|....|....:::|||:|||..|.|:
Worm   252 AKKRGDFTTYMLLLMVTVFLFTELPQGIMAILNALFTTQFHQMVYLNLADVLDLLSLINCYVAFL 316

  Fly   377 LYGLMSKQFRTTFRSL 392
            :|...|.::|.|..||
Worm   317 VYSFTSSRYRQTLFSL 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	93/327 (28%)
dmsr-6	NP_497004.1	7tmA_FMRFamide_R-like	33..329	CDD:320109	91/325 (28%)
		TM helix 1	34..58	CDD:320109	9/23 (39%)
		TM helix 2	67..89	CDD:320109	7/21 (33%)
		TM helix 3	109..131	CDD:320109	6/21 (29%)
		TM helix 4	152..168	CDD:320109	4/16 (25%)
		TM helix 5	207..230	CDD:320109	6/22 (27%)
		TM helix 6	257..282	CDD:320109	11/24 (46%)
		TM helix 7	297..322	CDD:320109	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28978
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46273
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.980