DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and dmsr-13

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_504730.1	Gene:	dmsr-13 / 188522	WormBaseID:	WBGene00020524	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	86/363 - (23%)
Similarity:	148/363 - (40%)	Gaps:	92/363 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 WL-----RAYNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVAD-------- 119
            ||     :||...|.|:...:.:|...|||:.:.||:.|||.::.:|..:..:||.|
Worm    29 WLITTVVKAYRPFHYYILTFLVVFAFFANIMIVKVLSHKEMIRSGVNVTMLLIAVCDFGCSIAGL 93

  Fly   120 --MFVMLEYIPYTSYQYIYMGPGEKDLSYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAI- 181
              :|:......||||...|   |:..:.|. ||.          .|..|:.|.|.:|..|..::
Worm    94 LQLFLRSYSDNYTSYPTAY---GQIAVDYL-AVA----------FHASSLYLAVGMAFCRVKSLN 144

  Fly   182 ---------RHPN----GGCANFLLAHSREAILLPFILSPILCLPTYFVFQVRETYDVDKVNSEA 233
                     :.||    ..||               :.:|:..:.|:.:|       ::.|.:..
Worm   145 IANRNKDLWQSPNYAVRVACA---------------LCAPVFLIATFVLF-------INAVKNTE 187

  Fly   234 MYHVYFD-------KDSVLYRFNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNN 291
            ...:|.|       .:.:..:.:.....:..|:.||.:::|:|..|:        ||:      :
Worm   188 EEGIYLDISDLSLLSECLFMKASLMASGLCFKIAPCLLMLVLSLFLL--------RRI------D 238

  Fly   292 PAKYAIQLNLNETKSKKPPRCDRRNDRTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCY 356
            ..|.:.|......|.||.     :.||::..:..|||:|||||.|||:..:|.|.|...:..: :
Worm   239 EGKQSAQNAAANQKGKKD-----KIDRSSRFIQFVLVVFLITESPQGVFSILGGFMILDYINY-F 297

  Fly   357 PPFGELMDLLALINAAVGFVLYGLMSKQFRTTFRSLFM 394
            ......|::||..|....|::|..:|.:||..|..||:
Worm   298 QNLSIFMNILAFFNTTTSFIIYSSLSAKFRRIFAQLFL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	79/345 (23%)
dmsr-13	NP_504730.1	7tmA_FMRFamide_R-like	40..330	CDD:320109	79/345 (23%)
		TM helix 1	42..66	CDD:320109	8/23 (35%)
		TM helix 2	75..97	CDD:320109	4/21 (19%)
		TM helix 3	115..137	CDD:320109	7/32 (22%)
		TM helix 4	161..177	CDD:320109	4/30 (13%)
		TM helix 5	208..228	CDD:320109	3/19 (16%)
		TM helix 6	259..284	CDD:320109	13/24 (54%)
		TM helix 7	298..323	CDD:320109	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.870