Protein Alignment CG13229 and srw-44

DIOPT Version :10

• Sequence 1: NP_610637.1
• Gene: CG13229 / 36168
• FlyBaseID: FBgn0033579
• Length: 414
• Species: Drosophila melanogaster
• Sequence 2: NP_507223.1
• Gene: srw-44 / 184480
• WormBaseID: WBGene00005791
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 367
• Identity: 80/367 - (21%)
• Similarity: 140/367 - (38%)
• Gaps: 78/367 - (21%)

  Fly    80 SLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADM------FVMLEYIPYTSYQYIYMG 138
            ||:|...|...||.::.|||||.|....::..|..:|:.|.      .|.|..|.|..|..:::.
 Worm    45 SLVIAFVGFFGNIFHLAVLTRKSMRILSVSTFLISIAICDFVRMMSTIVTLSPIFYREYLSLHVR 109

  Fly   139 -PGEKDLSYTWAVCLLVHMHFTQILH---TISIGLTVTLAV----WRYVAIRHP-NGGCANFLLA 194
             ..:...||       :.|:...:.|   |:|:.|:|..||    :|.:|||:| |....:.:.:
 Worm   110 LKCQPPPSY-------LEMYIIYVFHSLETVSMNLSVWFAVFMTIFRALAIRYPLNKRIKSLITS 167

  Fly   195 HSR--EAILLPFILSPILCLPTYF--VFQVRETY------DVDKVNSEAMYHVY---------FD 240
            .|.  ..|.:..::.|..||..:.  :|.....|      ...|..::..|.:.         .:
 Worm   168 ESGLCTVITITILILPFCCLSFFLRTLFPASTWYPSPGCKKFSKGYTQIQYRLLATELSGELGTE 232

  Fly   241 KDSVLYRFNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETK 305
            ...::.:    :..:|.|.||..:|.:                         |.:|:...:.:.|
 Worm   233 TSEIMQK----VEGLLFKFLPSVVLSL-------------------------ATFALVFAIRKHK 268

  Fly   306 SKKPPRCDRRN----DRTTLLLVAVLVLFLITEFPQGLLGLLS-GVMEKCFFAHCYPPFGELMDL 365
            .|   .|...|    ::||.|:..|...|||...|||:|.::. .|.|..............:..
 Worm   269 KK---NCTPGNKSDKEKTTKLVSFVTFTFLIAIVPQGILFMIMFKVFETSMMGAVIDELSTALSF 330

  Fly   366 LALINAAVGFVLYGLMSKQFRTTFRSLFMKRHFGSTEMTRLT 407
            |::||..:..::...|..::|.|.|.:|.::...|.....||
 Worm   331 LSVINGTIHLLIIYFMCSEYRKTIRCMFCRKSKPSISAITLT 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_610637.1	7tmA_FMRFamide_R-like	75..389	CDD:410630	74/347 (21%)
		TM helix 1	75..101	CDD:410630	9/20 (45%)
		TM helix 2	108..133	CDD:410630	7/30 (23%)
		TM helix 3	152..182	CDD:410630	10/36 (28%)
		TM helix 4	194..214	CDD:410630	5/21 (24%)
		TM helix 5	246..271	CDD:410630	5/24 (21%)
		TM helix 6	314..344	CDD:410630	12/33 (36%)
		TM helix 7	357..382	CDD:410630	3/24 (13%)
srw-44	NP_507223.1	TM helix 1	40..66	CDD:410630	9/20 (45%)
		7TM_GPCR_Srw	44..361	CDD:402097	77/354 (22%)
		TM helix 2	73..98	CDD:410630	5/24 (21%)
		TM helix 3	124..154	CDD:410630	9/29 (31%)
		TM helix 4	168..188	CDD:410630	4/19 (21%)
		TM helix 5	234..259	CDD:410630	6/53 (11%)
		TM helix 6	282..308	CDD:410630	11/25 (44%)
		TM helix 7	322..347	CDD:410630	3/24 (13%)