DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and dmsr-16

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001343685.1	Gene:	dmsr-16 / 13213403	WormBaseID:	WBGene00194821	Length:	328	Species:	Caenorhabditis elegans

Alignment Length:	359	Identity:	85/359 - (23%)
Similarity:	150/359 - (41%)	Gaps:	68/359 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 YNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADM------FVMLEYIPYT 130
            |..:|.|:...:.:....||.|..:||..|.|..:..|.|:.::::.|.      ...|....||
Worm     3 YRPVHHYILASLIVLSFFANALIAIVLANKVMRISGTNIIMLFISICDFGCSVSGLFQLFLRSYT 67

  Fly   131 SYQYIYMGP-GEKDLSYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLA 194
            .....|.|. |:..:.|. |||          .||.|:.....:|:.|.:::...|..      .
Worm    68 GEYNSYFGAYGQLIVDYL-AVC----------FHTSSLYAASGMALCRVMSLTLSNKN------R 115

  Fly   195 HS----REAILLPFILS-PILCLPT--YFVFQVRETYDVDKVNSEAMYHVYFD---KDSVLY-RF 248
            |.    :.|:.:...:| |:..|.|  .|:..|:|:.:      :.:|....|   .:..|| :.
Worm   116 HQWNTPKYALQVACCMSAPVFILATAVLFINSVKESQE------DGIYMEISDLSIANECLYMKI 174

  Fly   249 NFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKKPPRCD 313
            |..|..:..||.||..::::|.:|:.                       :::..:..:....|.|
Worm   175 NLAILGICFKLAPCISMLMLSVLLLQ-----------------------KMDQGKQSASNSTRKD 216

  Fly   314 RRN--DRTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFV 376
            .|.  ||::..:..||::|||||||||:..|| |.:....:.:.|......|::|:..|....|:
Worm   217 TRGKIDRSSSFIQFVLIVFLITEFPQGVFNLL-GALSIVDYLNYYQNLSIFMNVLSFFNTTTSFI 280

  Fly   377 LYGLMSKQFRTTFRSLFM-KRHFGSTEMTRLTRV 409
            :|..:|::||..|..||: ||....:.:.|.|.:
Worm   281 IYSALSEKFRRLFVQLFLPKRIIPQSLLNRRTLI 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	77/334 (23%)
dmsr-16	NP_001343685.1	7tmA_FMRFamide_R-like	5..293	CDD:320109	77/334 (23%)
		TM helix 1	7..31	CDD:320109	7/23 (30%)
		TM helix 2	40..62	CDD:320109	3/21 (14%)
		TM helix 3	80..102	CDD:320109	7/32 (22%)
		TM helix 4	126..142	CDD:320109	4/15 (27%)
		TM helix 5	173..196	CDD:320109	6/22 (27%)
		TM helix 6	222..247	CDD:320109	13/24 (54%)
		TM helix 7	261..286	CDD:320109	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870