DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13229 and gpr139

DIOPT Version :9

Sequence 1:	NP_001260880.1	Gene:	CG13229 / 36168	FlyBaseID:	FBgn0033579	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001308927.1	Gene:	gpr139 / 100493863	XenbaseID:	XB-GENE-6042001	Length:	348	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	78/327 - (23%)
Similarity:	149/327 - (45%)	Gaps:	65/327 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 YVSLMICIFGTIANILNIMVLTR--KEMAKTPINNILKWLAVADMFVM--LEYIPYTSYQYIYMG 138
            |.|:::|: |..||||.:::|::  ....|:..|.:|. ||.||:.|:  :.::.:....:|.
Frog    27 YYSILLCL-GLPANILTVIILSQLVARRQKSSYNYLLA-LAAADIMVLFFIVFVDFLLEDFIL-- 87

  Fly   139 PGEKDLSYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREAILLP 203
              .|.:.......:.| :.|:.| || ||.:||.|.:.||:|:.||.........|.:|:.|:..
Frog    88 --NKQMPQMLDKIIEV-LEFSSI-HT-SIWITVPLTIDRYIAVCHPLTYHTVSFPARTRKVIVSV 147

  Fly   204 FILSPILCLPTYFVFQVRETYDVDKVNSEAMYHVYFDKDSVLYRFNFWIHSVLIKLLPCGILIVI 268
            :|...:..:|.|:...:.    ::...|.:::|:.           .|||...:.|:||.|..|:
Frog   148 YITCFLTSIPYYWWPNIW----IEDYTSTSVHHIL-----------IWIHCFTVYLVPCSIFFVL 197

  Fly   269 SAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKKPPRCDRRNDRTTLLLVAVLVLFLIT 333
            ::::::.|...|  ..:||.|:                         ..:||.:|.::..:|.|.
Frog   198 NSIIVYKLQRKS--NFRLRGYS-------------------------TGKTTAILFSITSIFAIL 235

  Fly   334 EFPQGLL---GLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFVLYGLMSKQFRT----TFRS 391
            ..|:.::   .|....:...:..|...   ::.::|||:|.|:.|.||..:||:|||    |.::
Frog   236 WAPRIIMILYHLYVSPIHNSWLVHIVT---DIANMLALLNTAINFFLYCFISKRFRTMAAGTLKA 297

  Fly   392 LF 393
            .|
Frog   298 FF 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13229	NP_001260880.1	7tm_4	78..393	CDD:304433	77/325 (24%)
gpr139	NP_001308927.1	7tmA_GPR139	22..291	CDD:320585	76/317 (24%)
		TM helix 1	23..49	CDD:320585	9/22 (41%)
		TM helix 2	57..82	CDD:320585	7/25 (28%)
		TM helix 3	96..126	CDD:320585	13/32 (41%)
		TM helix 4	138..158	CDD:320585	4/19 (21%)
		TM helix 5	175..200	CDD:320585	9/35 (26%)
		TM helix 6	216..248	CDD:320585	7/56 (13%)
		TM helix 7	259..284	CDD:320585	9/27 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4738
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343117at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060