DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment BBS4 and kdm6a

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_005167851.1 Gene:kdm6a / 569277 ZFINID:ZDB-GENE-081105-56 Length:1452 Species:Danio rerio


Alignment Length:486 Identity:99/486 - (20%)
Similarity:161/486 - (33%) Gaps:155/486 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 NPEYLYFVQGLIDREEGNHIEALRHLQKSAELNP--------RNIETYKEIGRTLYIMGRFSQAL 121
            |..:||.: ||:    ..|..|.|.   :.:|.|        |.|:.::|:   |||...||:| 
Zfish   131 NAAFLYGL-GLV----YFHYNAFRW---AVQLTPSDAQSGQRRAIKAFQEV---LYIDPCFSRA- 183

  Fly   122 GVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQKDVASQQQDEARTYFELAVQSG-----RKLE 181
                          .||:..|| |:::..|          ..:.:..:|:||:...     .|.|
Zfish   184 --------------KEIHLRLG-LMFKVNT----------DYESSLKHFQLALIDSTPCTLSKAE 223

  Fly   182 SYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLK--INETQKAHDRLAEVVSIE 244
            ....:|.:|...|:|:.|.|..|:.|.  .||....::.:.|...  ::.|.:.....|...|..
Zfish   224 IQFHIAHVYEIQKKYRIAKEAYESLLQ--TENLPAQVKATTLQQLGWMHHTVEQLGDKANKNSYA 286

  Fly   245 RKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKS 309
            .:|..|.|                        .|:|...:.|..:|.|:....|...|..|.|:|
Zfish   287 IQCLQKSL------------------------EADPNSGQSWYFLGRCYSSIGKVQDAFISYRQS 327

  Fly   310 VWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLRKDNAECYMLLGL--------------- 359
            :..|..:.:...::.::|....|...|......|:.|...:|..:|.||.               
Zfish   328 IDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHSH
AAAWMDLGTLYESCNQPQDAIKCY 392

  Fly   360 --------------------CLR---------KLDDMENAFVALERASSM-----ATGQQGAGRN 390
                                ||:         .|........::|.|.|:     .|.:|||   
Zfish   393 INATCSKSCSNIPALTARIKCLQAQLCNLQQGSLPSKSKMLPSIEEAWSLPIPAELTSRQGA--- 454

  Fly   391 PLVVLNFALFCYETGRLALSTEQYNRFMSQAQDLLLP-------TEYKFQATKLKSLLRISNQGN 448
                ||..     ..:......|.|...||.....||       ||.:....|.|   |.::...
Zfish   455 ----LNTT-----QQQTTCKAHQSNEAQSQIPSQSLPPHVLSGQTEDQSSPAKKK---RTTSPAR 507

  Fly   449 GILLDSADMGESDLGHNRAT--ELLPDELPL 477
                :|:|...:|.||::.:  .|.|.:|.|
Zfish   508 ----NSSDSWTNDPGHHQISNWSLTPQKLQL 534

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160 19/69 (28%)
TPR repeat 68..95 CDD:276809 7/26 (27%)
TPR_12 97..175 CDD:290160 19/85 (22%)
TPR repeat 100..130 CDD:276809 8/29 (28%)
TPR repeat 136..175 CDD:276809 9/38 (24%)
TPR repeat 179..209 CDD:276809 10/29 (34%)
TPR_19 190..254 CDD:291240 16/65 (25%)
TPR repeat 214..242 CDD:276809 3/29 (10%)
TPR repeat 249..277 CDD:276809 2/27 (7%)
TPR_11 283..348 CDD:290150 14/64 (22%)
TPR repeat 283..311 CDD:276809 8/27 (30%)
TPR repeat 316..346 CDD:276809 4/29 (14%)
TPR repeat 351..377 CDD:276809 8/69 (12%)
kdm6aXP_005167851.1 TPR 74..332 CDD:223533 57/263 (22%)
TPR repeat 95..123 CDD:276809
TPR repeat 131..176 CDD:276809 14/55 (25%)
TPR repeat 181..211 CDD:276809 10/55 (18%)
TPR repeat 222..250 CDD:276809 8/27 (30%)
TPR repeat 260..295 CDD:276809 7/58 (12%)
TPR_17 289..320 CDD:290167 9/54 (17%)
TPR_11 302..365 CDD:290150 13/62 (21%)
TPR repeat 302..329 CDD:276809 8/26 (31%)
TPR repeat 334..364 CDD:276809 4/29 (14%)
TPR_1 335..368 CDD:278916 5/32 (16%)
TPR repeat 369..395 CDD:276809 4/25 (16%)
SSDP 572..852 CDD:282372
JmjC 1149..1213 CDD:214721
JmjC 1183..1291 CDD:202224
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.