DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and kdm6al

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_005168853.1 Gene:kdm6al / 569207 ZFINID:ZDB-GENE-070112-2002 Length:1356 Species:Danio rerio


Alignment Length:461 Identity:95/461 - (20%)
Similarity:157/461 - (34%) Gaps:101/461 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 RCRRLIERELNRHLNPEYLYFVQGLIDREEGNHIEALRHLQKSAELNPRNIETYKE--------- 106
            ||...:..:....::||  :|.|             |.|.....|..|:.:..|:.         
Zfish    78 RCYESLILKAEGKVDPE--FFCQ-------------LGHFNLLLEEYPKALSAYQRYYSLQSDYW 127

  Fly   107 --------IGRTLYIMGRFSQALGVFREA---EQRSSRQDHEIYHYLGELLYRAATTQSQKDVAS 160
                    :|...:....|..|:..|:|.   :...||. .||:..|| |:::..|         
Zfish   128 KNAAFLYGLGMVYFHYNAFQWAIKAFQEVLYIDPGFSRA-KEIHLRLG-LMFKVNT--------- 181

  Fly   161 QQQDEARTYFELA-VQSGR----KLESYVRLAELYRKDKQYQKAIEILENCLHL----TPENSEV 216
             ..:.:..:|:|| :.|.|    |.|....:|.||...|:::.|.|..|:.|..    ||..:..
Zfish   182 -DYESSLKHFQLALIDSSRCTLSKAEIQFHIAHLYEIQKRHRAAKEAYESLLQTEDLQTPVRAAA 245

  Fly   217 LIEISVLYLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPE 281
            |.::..::   :..::..|: |...|...:|..|.|                        .|:|.
Zfish   246 LQQLGWMH---HTVEQLGDK-ANKDSYAIQCLQKSL------------------------EADPN 282

  Fly   282 IAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINL 346
            ..:.|..:|.|:....|...|..|.|:|:..|..:.:...::.::|....|...|......|:.|
Zfish   283 SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQL 347

  Fly   347 RKDNAECYMLLGLCLRKLDDMENAFVALERASSMATGQQGAGRNPLVVLNFALFCYETGRLALST 411
            ...:|..:|.||......:...:|......|:...|....|.....:....|.||    :|.|::
Zfish   348 DHSHAAAWMDLGTLYESCNQPHDAIKCYINATRSKTCSNTAALAARIKYLQAQFC----KLRLNS 408

  Fly   412 EQYNR----FMSQAQDLLLPTEYKFQATKLKSLLRISNQGNGILLDSADMGESDLGHNRATELLP 472
            .|...    .:.:|..|.:|.|       |.|  |...|..|.....|..|.|......|..|.|
Zfish   409 LQGKSKTLPNIEEAWSLPIPAE-------LTS--RQGVQSTGPQACKAQPGASSGSQASAPALPP 464

  Fly   473 DELPLE 478
            ....||
Zfish   465 HSTALE 470

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160 13/80 (16%)
TPR repeat 68..95 CDD:276809 4/26 (15%)
TPR_12 97..175 CDD:290160 18/98 (18%)
TPR repeat 100..130 CDD:276809 6/49 (12%)
TPR repeat 136..175 CDD:276809 9/39 (23%)
TPR repeat 179..209 CDD:276809 10/29 (34%)
TPR_19 190..254 CDD:291240 15/67 (22%)
TPR repeat 214..242 CDD:276809 3/27 (11%)
TPR repeat 249..277 CDD:276809 2/27 (7%)
TPR_11 283..348 CDD:290150 14/64 (22%)
TPR repeat 283..311 CDD:276809 8/27 (30%)
TPR repeat 316..346 CDD:276809 4/29 (14%)
TPR repeat 351..377 CDD:276809 5/25 (20%)
kdm6alXP_005168853.1 TPR_11 92..161 CDD:290150 14/83 (17%)
TPR repeat 93..121 CDD:276809 9/42 (21%)
TPR_11 129..194 CDD:290150 15/76 (20%)
TPR repeat 129..159 CDD:276809 5/29 (17%)
TPR_1 130..163 CDD:278916 5/32 (16%)
TPR repeat 164..194 CDD:276809 10/41 (24%)
TPR repeat 205..233 CDD:276809 8/27 (30%)
TPR repeat 243..278 CDD:276809 7/62 (11%)
TPR_17 272..303 CDD:290167 9/54 (17%)
TPR_11 285..348 CDD:290150 13/62 (21%)
TPR repeat 285..312 CDD:276809 8/26 (31%)
TPR repeat 317..347 CDD:276809 4/29 (14%)
TPR_1 318..351 CDD:278916 5/32 (16%)
TPR repeat 352..378 CDD:276809 5/25 (20%)
JmjC 1053..1117 CDD:214721
JmjC 1087..1195 CDD:202224
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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