DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and spag1a

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_001082875.2 Gene:spag1a / 564953 ZFINID:ZDB-GENE-030131-9443 Length:386 Species:Danio rerio


Alignment Length:318 Identity:77/318 - (24%)
Similarity:123/318 - (38%) Gaps:59/318 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 PRNIETYKEIGRTLYIMGRFSQALGVFREAEQR------SSRQDHEIYHYLGELLY--RAATTQS 154
            |..:...|..|..|:..|:|..||..:.:|...      .|.:|..:       ||  |||....
Zfish    81 PPPLARLKNQGNMLFKNGQFGDALEKYTQAIDGCIEAGIDSPEDLCV-------LYSNRAACFLK 138

  Fly   155 QKDVASQQQDEARTYFELAVQSGRKLESYVRLAELYRKDKQYQKA---------IEILENCLH-- 208
            ..:.|...||..|. .||...|   |:..:|.|..|...::|:||         |:|.....|  
Zfish   139 DGNSADCIQDCTRA-LELHPFS---LKPLLRRAMAYESLERYRKAYVDYKTVLQIDISVQAAHDS 199

  Fly   209 ---LT--------PENSEVLIEISVLYLKINETQKAHDRLAEVVS-----IERKCSPKGLLAFGA 257
               :|        |:..|.|.||..:.|...:.:| .:..||::.     .|::.:.|....|..
Zfish   200 VHRITKMLIEQDGPDWREKLPEIPAVPLSAQQHRK-EEPSAELLQARAERAEQEKARKAEARFTI 263

  Fly   258 ILQSRNDI------DGALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLN 316
            :.|..|::      .||..|||:....:|....::.|..|||.|.::|..|......::.:.|.|
Zfish   264 LKQEGNELVKNSQFQGASEKYSECLAIKPNECAIYTNRALCFLKLERFAEAKQDCDSALQMEPKN 328

  Fly   317 YNALYNLSLIYIASEQYASAFHTLAAAI----NLRKDNAECYMLLGLCLRKLDDMENA 370
            ..|.|..:|.:...:.|.||...|...:    |:::...|..|:..|....|  :.||
Zfish   329 KKAFYRRALAHKGLKDYLSASTDLQEVLQLDPNVQEAEQELEMVTNLLRESL--LANA 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160 8/28 (29%)
TPR repeat 68..95 CDD:276809
TPR_12 97..175 CDD:290160 22/84 (26%)
TPR repeat 100..130 CDD:276809 8/29 (28%)
TPR repeat 136..175 CDD:276809 11/40 (28%)
TPR repeat 179..209 CDD:276809 10/43 (23%)
TPR_19 190..254 CDD:291240 19/90 (21%)
TPR repeat 214..242 CDD:276809 8/27 (30%)
TPR repeat 249..277 CDD:276809 9/33 (27%)
TPR_11 283..348 CDD:290150 17/68 (25%)
TPR repeat 283..311 CDD:276809 7/27 (26%)
TPR repeat 316..346 CDD:276809 8/33 (24%)
TPR repeat 351..377 CDD:276809 6/20 (30%)
spag1aNP_001082875.2 TPR_11 87..157 CDD:290150 21/77 (27%)
TPR repeat 87..112 CDD:276809 8/24 (33%)
TPR repeat 125..155 CDD:276809 9/37 (24%)
TPR_11 128..190 CDD:290150 19/65 (29%)
TPR repeat 160..188 CDD:276809 7/27 (26%)
TPR_11 263..326 CDD:290150 15/62 (24%)
TPR repeat 263..289 CDD:276809 7/25 (28%)
TPR repeat 294..324 CDD:276809 7/29 (24%)
TPR_11 297..360 CDD:290150 16/62 (26%)
TPR_1 297..328 CDD:278916 8/30 (27%)
TPR repeat 329..357 CDD:276809 7/27 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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