DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and tmtc2a

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_001124075.1 Gene:tmtc2a / 564667 ZFINID:ZDB-GENE-041210-299 Length:844 Species:Danio rerio


Alignment Length:262 Identity:52/262 - (19%)
Similarity:103/262 - (39%) Gaps:45/262 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 YFVQGLIDREEGNHIEALRHLQKSAELNPRNIE---TYK--------EIGRTLYIMGRFSQALGV 123
            |...|:|...:||..||.|.....|::...|::   .:|        .:|:.|:..|:..:||.|
Zfish   572 YLNVGIILVSQGNIEEAKRTFHTCADIPDENLKDPHAHKSSVTSCLYNLGKLLHDQGQHEEALSV 636

  Fly   124 FREAEQRSSRQ--DHEIYHYLGELL------------YRAATTQSQKDVASQ-----------QQ 163
            ::||.::..||  ...:|:.:||..            ||.:.......:.:.           |:
Zfish   637 YKEAVRKMPRQFAPQSLYNMMGEAYMRLNILEEAGHWYRESLKAKPDHIPAHLTYGKLLSIMGQK 701

  Fly   164 DEARTYFELAVQ-SGRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLKI 227
            .||..||..|:: ...:...|:...:...::.:..:|..:.:....|..|..:|:...:.:..:.
Zfish   702 SEAERYFLKAIELDP
ARGNCYMHYGQFLLEESRLAEAAAMAQKAAELDNEEFDVVFSAAHMLRQA 766

  Fly   228 NETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPE-------IAEL 285
            :..::|.....:...: |...|..|:..||||.....:..|.|.|.:....:|:       :.:|
Zfish   767 SLNEEAETYYGKAADL-RPDHPAALMNLGAILHLNGKLKEAESNYLRALQLKPDD
LITQSNLHKL 830

  Fly   286 WN 287
            ||
Zfish   831 WN 832

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160 17/67 (25%)
TPR repeat 68..95 CDD:276809 8/24 (33%)
TPR_12 97..175 CDD:290160 23/113 (20%)
TPR repeat 100..130 CDD:276809 10/40 (25%)
TPR repeat 136..175 CDD:276809 11/61 (18%)
TPR repeat 179..209 CDD:276809 2/29 (7%)
TPR_19 190..254 CDD:291240 8/63 (13%)
TPR repeat 214..242 CDD:276809 2/27 (7%)
TPR repeat 249..277 CDD:276809 9/27 (33%)
TPR_11 283..348 CDD:290150 3/5 (60%)
TPR repeat 283..311 CDD:276809 3/5 (60%)
TPR repeat 316..346 CDD:276809
TPR repeat 351..377 CDD:276809
tmtc2aNP_001124075.1 DUF1736 254..328 CDD:285594
TPR_11 501..562 CDD:290150
TPR repeat 501..529 CDD:276809
TPR_1 501..>528 CDD:278916
TPR repeat 534..564 CDD:276809
TPR_1 535..>562 CDD:278916
TPR_12 565..642 CDD:290160 19/69 (28%)
TPR repeat 569..597 CDD:276809 8/24 (33%)
TPR repeat 603..642 CDD:276809 9/38 (24%)
TPR_2 617..646 CDD:285020 8/28 (29%)
TPR_11 653..716 CDD:290150 11/62 (18%)
TPR repeat 653..679 CDD:276809 5/25 (20%)
TPR repeat 684..714 CDD:276809 6/29 (21%)
TPR_8 685..716 CDD:289924 6/30 (20%)
TPR_16 757..820 CDD:290168 12/63 (19%)
TPR_1 787..820 CDD:278916 10/32 (31%)
TPR repeat 787..815 CDD:276809 9/27 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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