DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and Ttc16

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_796358.2 Gene:Ttc16 / 338348 MGIID:2443048 Length:824 Species:Mus musculus


Alignment Length:339 Identity:79/339 - (23%)
Similarity:127/339 - (37%) Gaps:69/339 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 YFELAVQSGRKL-ESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEIS-VLYL------ 225
            :|..|:....|| :.||..||.:.:...:..|::.|.......|.|::.|..:: ||||      
Mouse    97 FFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCLY 161

  Fly   226 KINETQ-------KAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEI- 282
            ::.:.|       :|.|...:..|...:|     :|....|:..:|....:::..:...|..:: 
Mouse   162 ELCDFQEALCVFLQASDLQPQNASFSYRC-----MACLLALKRYHDCLALITREVKQGRASADVY 221

  Fly   283 ---AELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAA-- 342
               |.|:|     ||:|.|  :....||.::.|.||:..|...|..:...::|......|||.  
Mouse   222 ILRARLYN-----FFQKAK--LCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDASTLAVQG 279

  Fly   343 -------AINLRKDN----AECYMLLGLCLRKLDDMENAFVALERASSMATGQQG-----AGRNP 391
                   .||...:|    ...:...|...|:|...::|.....:|..|.|..|.     |.|..
Mouse   280 KVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQL 344

  Fly   392 LVVLN-FALFCYETG---------RLALSTEQ------YNR---FMSQAQDLLLPTEYKFQATKL 437
            |:..| ||:.||..|         ..|:..||      .||   |...........:|| ||..|
Mouse   345 LLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYK-QALAL 408

  Fly   438 KSLLRISNQGNGIL 451
            ..|...:|...|:|
Mouse   409 SPLDEGANLRMGVL 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160
TPR repeat 68..95 CDD:276809
TPR_12 97..175 CDD:290160 2/5 (40%)
TPR repeat 100..130 CDD:276809
TPR repeat 136..175 CDD:276809 2/5 (40%)
TPR repeat 179..209 CDD:276809 8/30 (27%)
TPR_19 190..254 CDD:291240 14/77 (18%)
TPR repeat 214..242 CDD:276809 8/41 (20%)
TPR repeat 249..277 CDD:276809 3/27 (11%)
TPR_11 283..348 CDD:290150 20/73 (27%)
TPR repeat 283..311 CDD:276809 9/27 (33%)
TPR repeat 316..346 CDD:276809 7/38 (18%)
TPR repeat 351..377 CDD:276809 4/25 (16%)
Ttc16NP_796358.2 TPR repeat 75..103 CDD:276809 2/5 (40%)
TPR 87..381 CDD:223533 67/295 (23%)
TPR repeat 108..138 CDD:276809 7/29 (24%)
TPR repeat 143..170 CDD:276809 6/26 (23%)
TPR repeat 183..213 CDD:276809 5/34 (15%)
TPR repeat 218..245 CDD:276809 9/33 (27%)
TPR repeat 299..327 CDD:276809 5/27 (19%)
TPR repeat 347..373 CDD:276809 7/25 (28%)
TPR repeat 378..408 CDD:276809 7/30 (23%)
TPR_11 381..451 CDD:290150 12/43 (28%)
TPR_1 382..410 CDD:278916 8/28 (29%)
TPR repeat 413..448 CDD:276809 3/10 (30%)
TPR_11 426..485 CDD:290150
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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