Protein Alignment BBS4 and Ifit2

DIOPT Version :9

• Sequence 1: NP_610636.1
• Gene: BBS4 / 36167
• FlyBaseID: FBgn0033578
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001019924.1
• Gene: Ifit2 / 294091
• RGDID: 1307804
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 491
• Identity: 103/491 - (20%)
• Similarity: 183/491 - (37%)
• Gaps: 121/491 - (24%)

  Fly    33 DANIDWLLHIYFTRREF-------TRCRRLIERELNRHLNPEYLYFVQGLIDREEGNHIEALRHL 90
            |.::|......|.:.||       |.|..|...:..|.||...|..:        |...:.:|.
  Rat    28 DESLDEFEDRVFNKDEFQNSEFKATMCNLLAYVKHCRGLNEAALKCL--------GEAEDFIRQ- 83

  Fly    91 QKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQ--RSSRQDHEIYHYLGELLYRAATTQ 153
            |...::..:::.|:.......|.||:.|:|.....:.:|  :.....:.|.:.:.:.....|..:
  Rat    84 QHPDQIEIKSLVTWGNYAWVYYHMGQLSKAQEYLDKVKQVCKKFSSPYRIENPVLDCEEGWARLK 148

  Fly   154 SQKDVASQQQDEARTYFELAVQ---------SGRKLESYVRLAELYRKDKQYQKAIEILENCLHL 209
            ..|:    |.:..:..||.|::         ||..:.:| ||.: :.....|   |:.||..:.|
  Rat   149 CTKN----QNERMKVCFEKALEKDPKNPESTSGWAIANY-RLDD-WPASNDY---IDSLEQAISL 204

  Fly   210 TPENSEVLIEISVLYLKINETQKAHDRLAEVVSIERKCSPKG---LLAFGAILQSRNDIDGALSK 271
            :|:|:.|.:   :|.:|:.|..:  :|..|:|....|..|..   :|.........:|.|.|:..
  Rat   205 SPDNTYVKV---LLAMKLEEVHE--NRAKELVEEALKKDPSAIDTMLGAAKFYVKVHDTDRAIQL 264

  Fly   272 YSQIANAEPEIAELWNNIGLCFFKKQKFIV--------------------AISSLRKSVWLSPLN 316
            ..:...:.|..|.:...:|.|:..|...|:                    |::.|||:..:..:.
  Rat   265 LKKALESMPNNAYVHYYLGCCYRSKVLHILNTEETTSNGNREKLEALIQPALNHLRKAEDIKEMI 329

  Fly   317 YNALYNLSLIYIASEQYASAFHTLAAAIN------------LRKDNAECYMLLGLCLRKLDD--- 366
            .|:..:|:.:|:.::||..|.:......|            ||..|.:.|.      ||.:|
  Rat   330 ENSCSHLAGLYVTTKQYEEADYYFQKEFNKDLRPLPKQLLHLRYGNFQFYE------RKCEDRAI 388

  Fly   367 ---MENAFVALERASSMATGQQGAGRNPLVVLNFALFCYETGRLALSTEQYNRFMSQAQDLLLPT 428
               ||.  |.:.|.|.    .:|..|:.|            .:|||      |.:|:       .
  Rat   389 YHYMEG--VKINRESK----PKGKMRDKL------------RKLAL------RRLSR-------D 422

  Fly   429 EYKFQATKLKSLLRISNQGNGILLDSADMGESDLGH 464
            |...:|.::.:.||...:|.|  .|.|..||.|.|:
  Rat   423 ESDPEALRILAFLREHREGQG--ADKASEGEEDPGN 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BBS4	NP_610636.1	TPR_12	63..127	CDD:290160	12/63 (19%)
		TPR repeat	68..95	CDD:276809	4/26 (15%)
		TPR_12	97..175	CDD:290160	14/79 (18%)
		TPR repeat	100..130	CDD:276809	7/31 (23%)
		TPR repeat	136..175	CDD:276809	7/38 (18%)
		TPR repeat	179..209	CDD:276809	7/29 (24%)
		TPR_19	190..254	CDD:291240	16/66 (24%)
		TPR repeat	214..242	CDD:276809	6/27 (22%)
		TPR repeat	249..277	CDD:276809	5/30 (17%)
		TPR_11	283..348	CDD:290150	17/96 (18%)
		TPR repeat	283..311	CDD:276809	9/47 (19%)
		TPR repeat	316..346	CDD:276809	7/41 (17%)
		TPR repeat	351..377	CDD:276809	7/31 (23%)
Ifit2	NP_001019924.1	TPR_12	51..126	CDD:290160	17/83 (20%)
		TPR repeat	96..122	CDD:276809	6/25 (24%)
		TPR repeat	127..167	CDD:276809	7/43 (16%)
		TPR repeat	242..270	CDD:276809	4/27 (15%)
		TPR repeat	275..325	CDD:276809	9/49 (18%)
		TPR repeat	330..355	CDD:276809	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900