DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and Tmtc4

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_006252585.1 Gene:Tmtc4 / 290501 RGDID:1560183 Length:773 Species:Rattus norvegicus


Alignment Length:293 Identity:60/293 - (20%)
Similarity:113/293 - (38%) Gaps:61/293 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 LNPEYLYFV-QGLIDREEGNHIEALRHLQKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREA 127
            ||.:..|.: :.|.|  :||...|:::.:::..|||:.:.....:|..|                
  Rat   512 LNAKVHYNIGKNLAD--QGNQTAAIKYYREAVRLNPKYVHAMNNLGNIL---------------- 558

  Fly   128 EQRSSRQDHEIYHYLGELLYRAATTQSQKDVAS------------QQQDEARTYFELAVQSGRKL 180
            ::|:..|:.|      |||  :...|.|.|.|:            ::.:||...:..|::..||.
  Rat   559 KERNELQEAE------ELL--SLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKY 615

  Fly   181 -ESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLKINETQKAHDRLAEVVSIE 244
             :.|..|..||....::..|:....|...:.||:|.....:.:|   ::.|    ..||:..::.
  Rat   616 PDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVIL---LDNT----GNLAQAEAVG 673

  Fly   245 RKC---SPKGLLAFGAILQSRNDIDGALSKYSQ-------IANAEPEIAELWNNIGLCFFKKQKF 299
            |:.   .|..    .:::.|..::.|...||.:       ...|.|.:|....|:.:.:.:....
  Rat   674 REALQLIPND----HSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHL 734

  Fly   300 IVAISSLRKSVWLSPLNYNALYNLSLIYIASEQ 332
            ..|......|:.|.|:......|.||:....||
  Rat   735 DSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQ 767

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160 13/63 (21%)
TPR repeat 68..95 CDD:276809 6/27 (22%)
TPR_12 97..175 CDD:290160 17/89 (19%)
TPR repeat 100..130 CDD:276809 2/29 (7%)
TPR repeat 136..175 CDD:276809 11/50 (22%)
TPR repeat 179..209 CDD:276809 7/30 (23%)
TPR_19 190..254 CDD:291240 12/66 (18%)
TPR repeat 214..242 CDD:276809 5/27 (19%)
TPR repeat 249..277 CDD:276809 5/34 (15%)
TPR_11 283..348 CDD:290150 11/50 (22%)
TPR repeat 283..311 CDD:276809 4/27 (15%)
TPR repeat 316..346 CDD:276809 5/17 (29%)
TPR repeat 351..377 CDD:276809
Tmtc4XP_006252585.1 DUF1736 324..398 CDD:285594
TPR 513..771 CDD:223533 59/292 (20%)
TPR_1 514..547 CDD:278916 9/34 (26%)
TPR repeat 514..542 CDD:276809 6/29 (21%)
TPR_17 536..569 CDD:290167 8/54 (15%)
TPR repeat 547..577 CDD:276809 8/53 (15%)
TPR_1 582..615 CDD:278916 5/32 (16%)
TPR repeat 582..610 CDD:276809 4/27 (15%)
TPR repeat 616..642 CDD:276809 5/25 (20%)
TPR repeat 650..678 CDD:276809 6/34 (18%)
TPR repeat 683..713 CDD:276809 4/33 (12%)
TPR_17 706..739 CDD:290167 5/32 (16%)
TPR repeat 718..746 CDD:276809 4/27 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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