DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and Spag1

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_001346910.1 Gene:Spag1 / 26942 MGIID:1349387 Length:913 Species:Mus musculus


Alignment Length:299 Identity:57/299 - (19%)
Similarity:102/299 - (34%) Gaps:96/299 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 AATTQSQKDVASQQQDEARTYFELAVQ-SGRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPE 212
            |...::|.::..|:...|....|.|:: ....:::.:|.|..|:...:.|:|::.|...|.:.|:
Mouse   260 AYNNRAQAEIKLQRWSSALEDCEKALELDPGNVKALLRRATTYKHQNKLQEAVDDLRKVLQVEPD 324

  Fly   213 N-------SEVLIE------ISVLYLK-----INETQKAHDR---------------LAEVVSIE 244
            |       |||..:      :|.|..|     |.|.:.:.|.               .|.:.:|:
Mouse   325 NDLAKKTLSEVERDLKNSEPVSELQTKGKRMVIEEVENSGDEGGKGSADEREDGGSDEAAMGNIQ 389

  Fly   245 RKC------------------------------------------------SPKGLLAFGAILQS 261
            :|.                                                :|.||...|..|..
Mouse   390 KKLMVRRSEGGRRSRRGRTPGPRAEQQGGLRETATASTGDSHYPEEPRAADNPSGLKRRGNELFR 454

  Fly   262 RNDIDGALSKYS-QIANAEP-------EIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYN 318
            ......|.::|| .||..||       |::.|::|...|:.|:......|....:::.|.|.:..
Mouse   455 GGQFAEAAAQYSVAIAQLEPTGSANADELSILYSNRAACYLKEGNCRDCIQDCNRALELHPFSVK 519

  Fly   319 ALYNLSLIYIASEQYASAF------HTLAAAINLRKDNA 351
            .|...::.|...|||.:|:      ..:...|.|..|:|
Mouse   520 PLLRRAMAYETLEQYRNAYVDYKTVLQIDCGIQLASDSA 558

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160
TPR repeat 68..95 CDD:276809
TPR_12 97..175 CDD:290160 6/25 (24%)
TPR repeat 100..130 CDD:276809
TPR repeat 136..175 CDD:276809 6/25 (24%)
TPR repeat 179..209 CDD:276809 7/29 (24%)
TPR_19 190..254 CDD:291240 22/144 (15%)
TPR repeat 214..242 CDD:276809 10/53 (19%)
TPR repeat 249..277 CDD:276809 9/28 (32%)
TPR_11 283..348 CDD:290150 15/70 (21%)
TPR repeat 283..311 CDD:276809 5/27 (19%)
TPR repeat 316..346 CDD:276809 7/35 (20%)
TPR repeat 351..377 CDD:276809 1/1 (100%)
Spag1NP_001346910.1 3a0801s09 214..698 CDD:273380 57/299 (19%)
TPR repeat 229..253 CDD:276809
TPR repeat 258..287 CDD:276809 6/26 (23%)
TPR repeat 292..320 CDD:276809 6/27 (22%)
TPR repeat 445..471 CDD:276809 7/25 (28%)
TPR repeat 483..513 CDD:276809 5/29 (17%)
TPR repeat 518..546 CDD:276809 6/27 (22%)
TPR repeat 619..646 CDD:276809
PLN03088 631..>807 CDD:215568
TPR repeat 651..681 CDD:276809
RPAP3_C 789..878 CDD:404718
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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