Protein Alignment BBS4 and Ttc13

DIOPT Version :10

• Sequence 1: NP_610636.1
• Gene: BBS4 / 36167
• FlyBaseID: FBgn0033578
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001360868.1
• Gene: Ttc13 / 234875
• MGIID: 2384573
• Length: 845
• Species: Mus musculus
• Alignment Length: 376
• Identity: 74/376 - (19%)
• Similarity: 131/376 - (34%)
• Gaps: 84/376 - (22%)

  Fly    91 QKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQ 155
            ||.......|..|.:|:.....::|.     |::.||          |.|:       :...|.:
Mouse   116 QKRFPFATDNDSTNEELAIAYVLVGS-----GLYDEA----------IRHF-------STMLQEE 158

  Fly   156 KDVASQQQDEARTY---------------FEL----AVQSGRKLESYVRLAELYRKDKQYQKAIE 201
            .|:.|........|               |||    |::..|. |.:.:.||:.....:..:|:.
Mouse   159 PDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRP-EVFEQRAEILSPLGRINEAVN 222

  Fly   202 ILENCLHLTPENSEVLIEISVLYLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDID 266
            .|...:.|.| ::.:......||....:...||:...:.:.:.|. .|..:|..|.....|..:.
Mouse   223 DLTKAIQLQP-SARLYRHRGTLYFISEDYATAHEDFQQSLELNRN-QPTAMLYKGLTFFHRGLLK 285

  Fly   267 GALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASE 331
            .|:..:.:....:.:..:.:.::|..:.:...|..|..|.:|::.   ||.|.:..|.|..:...
Mouse   286 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALL---LNQNHVQTLQLRGMMLY 347

  Fly   332 QYAS---AFHTLAAAINLRKDNAECYMLLGLCLRKLDDMENAFVALERASSMATGQ--QGAGRNP 391
            .:.|   |.......:.|...|..|..:.||                  |.:|.||  :|.....
Mouse   348 HHGSLQEALKNFKRCLQLEPYNEVCQYMKGL------------------SHVAMGQFYEGIKAQT 394

  Fly   392 LVVLNFALFCYETGRLALSTE--------QYNRFMSQAQDLLLPTEYKFQA 434
            .|:||..|    .|:.| |.|        :|:|::....|..| |||...:
Mouse   395 KVMLNDPL----PGQKA-SPEYLRVKYLREYSRYLHAHLDTPL-TEYNIDS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BBS4	NP_610636.1	TPR repeat	68..95	CDD:276809	2/3 (67%)
		LapB	70..347	CDD:442196	49/277 (18%)
		TPR repeat	100..130	CDD:276809	7/29 (24%)
		TPR repeat	136..175	CDD:276809	10/57 (18%)
		TPR repeat	179..209	CDD:276809	5/29 (17%)
		TPR repeat	214..242	CDD:276809	4/27 (15%)
		TPR repeat	249..277	CDD:276809	5/27 (19%)
		BepA	281..423	CDD:443813	32/154 (21%)
		TPR repeat	283..311	CDD:276809	5/27 (19%)
		TPR repeat	316..346	CDD:276809	6/32 (19%)
		TPR repeat	351..377	CDD:276809	3/25 (12%)
Ttc13	NP_001360868.1	BepA	116..232	CDD:443813	26/138 (19%)
		TPR repeat	132..156	CDD:276809	6/45 (13%)
		TPR repeat	164..195	CDD:276809	4/30 (13%)
		TPR	194..436	CDD:440225	55/271 (20%)
		TPR repeat	201..229	CDD:276809	5/28 (18%)
		TPR repeat	234..262	CDD:276809	4/27 (15%)
		TPR repeat	267..297	CDD:276809	5/29 (17%)
		TPR repeat	302..329	CDD:276809	5/26 (19%)
		TPR repeat	336..364	CDD:276809	4/27 (15%)
		TPR repeat	370..397	CDD:276809	8/44 (18%)