DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment BBS4 and Kdm6b

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_030101676.1 Gene:Kdm6b / 216850 MGIID:2448492 Length:1642 Species:Mus musculus


Alignment Length:331 Identity:64/331 - (19%)
Similarity:111/331 - (33%) Gaps:87/331 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 AVQSGRKLESYVRLAELYRKDKQYQKAIEILENCLHL--------------TPENSEVLIEISVL 223
            ::..|...|..:||.::...||:...|.|:.|..|.:              ..:|::|..:....
Mouse  1092 SLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVMRASKNAKVKGKFRES 1156

  Fly   224 YLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNN 288
            ||...::.|......|.:..|:...|...:    .|:|:.|   |.|         |.:.:...:
Mouse  1157 YLSPAQSVKPKINTEEKLPREKLNPPTPSI----YLESKRD---AFS---------PVLLQFCTD 1205

  Fly   289 IGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLRKDNAEC 353
                   .:..|..|..|..|:.|         ||.|....:...||..||:.....:::.:.|.
Mouse  1206 -------PRNPITVIRGLAGSLRL---------NLGLFSTKTLVEASGEHTVEVRTQVQQPSDEN 1254

  Fly   354 YMLLGL-----CLRKLDDMENAFVALERASSMATGQQ----------------GAGRNPLVV--- 394
            :.|.|.     |.........|..|..:|||.....|                ..|.:|...   
Mouse  1255 WDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQQEERESEDEESEEPDSTTGTSPSSAPDP 1319

  Fly   395 LNFALFCYETGRLALSTEQYNRFMSQAQDLLLPTEYKFQATKLKSLLRISNQGNGILLDSADMGE 459
            .|..:..:.|.   :......|:..|.|:||          ||.:.:|:::.||.:    :.:|.
Mouse  1320 KNHHIIKFGTN---IDLSDAKRWKPQLQELL----------KLPAFMRVTSTGNML----SHVGH 1367

  Fly   460 SDLGHN 465
            :.||.|
Mouse  1368 TILGMN 1373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160
TPR repeat 68..95 CDD:276809
TPR_12 97..175 CDD:290160 0/1 (0%)
TPR repeat 100..130 CDD:276809
TPR repeat 136..175 CDD:276809 0/1 (0%)
TPR repeat 179..209 CDD:276809 9/29 (31%)
TPR_19 190..254 CDD:291240 14/77 (18%)
TPR repeat 214..242 CDD:276809 5/27 (19%)
TPR repeat 249..277 CDD:276809 6/27 (22%)
TPR_11 283..348 CDD:290150 12/64 (19%)
TPR repeat 283..311 CDD:276809 4/27 (15%)
TPR repeat 316..346 CDD:276809 7/29 (24%)
TPR repeat 351..377 CDD:276809 6/30 (20%)
Kdm6bXP_030101676.1 TPR repeat 106..136 CDD:276809
JmjC 1342..1406 CDD:214721 13/46 (28%)
JmjC 1376..1484 CDD:396791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.