DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and Ttc24

DIOPT Version :9

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_766114.1 Gene:Ttc24 / 214191 MGIID:2443841 Length:334 Species:Mus musculus


Alignment Length:292 Identity:65/292 - (22%)
Similarity:107/292 - (36%) Gaps:77/292 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   258 ILQSR----NDIDGALSKYSQIANAEPE-----IAELWNNIGLCFFKKQKFIVAISSLRKSVWLS 313
            :|.||    :|:..||.:..::|:|:..     :...:|::|:.:|:.|.|.:|:.:..:::   
Mouse     1 MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQAL--- 62

  Fly   314 PL------NYNALYNLSLIYIASEQY--ASAFHTLAA----AINLRKDNAECYMLLGLCLRKLDD 366
            ||      ....|.||.:.:.....|  |..||..||    ::..|.:....:..|...|.:|.|
Mouse    63 PLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGD 127

  Fly   367 MENAFVALERASSMA--TGQ----------QGAGRNPLVVLNFALFCYETGRLALS--------- 410
            ...|:.:...|...|  ||.          .||....|...:.||..|:.. |||.         
Mouse   128 HRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEA-LALCQHEPSSVRE 191

  Fly   411 ------TEQYNRFMSQ---AQDLLLPT-EYKFQAT-KLKSLLRISNQGNGILLDSADMGESDLGH 464
                  .:....|::|   ||...||: ..|.|.: |.|:..|:.:..........:...|:.||
Mouse   192 RLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGH 256

  Fly   465 --------------------NRATELLPDELP 476
                                ||||..||...|
Mouse   257 EKKEMEGLVNTATVLGPQRQNRATTHLPSGGP 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR_12 63..127 CDD:290160
TPR repeat 68..95 CDD:276809
TPR_12 97..175 CDD:290160
TPR repeat 100..130 CDD:276809
TPR repeat 136..175 CDD:276809
TPR repeat 179..209 CDD:276809
TPR_19 190..254 CDD:291240
TPR repeat 214..242 CDD:276809
TPR repeat 249..277 CDD:276809 6/22 (27%)
TPR_11 283..348 CDD:290150 17/76 (22%)
TPR repeat 283..311 CDD:276809 6/27 (22%)
TPR repeat 316..346 CDD:276809 9/35 (26%)
TPR repeat 351..377 CDD:276809 5/25 (20%)
Ttc24NP_766114.1 TPR 1 35..68 8/35 (23%)
TPR repeat 38..66 CDD:276809 8/30 (27%)
TPR_12 68..144 CDD:290160 17/75 (23%)
TPR 2 72..105 9/32 (28%)
TPR repeat 72..100 CDD:276809 8/27 (30%)
TPR repeat 111..141 CDD:276809 6/29 (21%)
TPR 3 112..145 7/32 (22%)
TPR_12 113..183 CDD:290160 18/70 (26%)
TPR 4 152..185 9/33 (27%)
TPR_1 152..184 CDD:278916 9/32 (28%)
TPR repeat 152..180 CDD:276809 6/28 (21%)
TPR_12 158..214 CDD:290160 13/56 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 220..258 8/37 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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