DRSC/TRiP Functional Genomics Resources

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Protein Alignment BBS4 and Ifit3

DIOPT Version :10

Sequence 1:NP_610636.1 Gene:BBS4 / 36167 FlyBaseID:FBgn0033578 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_011245453.1 Gene:Ifit3 / 15959 MGIID:1101055 Length:434 Species:Mus musculus


Alignment Length:345 Identity:76/345 - (22%)
Similarity:132/345 - (38%) Gaps:83/345 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 GTEQINCNGRLIELPTLEVVRPAPKMPSDANIDWLLHIYFTRREFTRCRRLIERELNR--HLNPE 67
            |...::.:...:...:||.:.|..|    .:..|.|.     ||.:....:.:|..|:  |||.|
Mouse    24 GLGNVHDHANEVNRESLEAILPQLK----CHFTWNLF-----REGSMSSHMEDRVCNQVEHLNSE 79

  Fly    68 ---YLYFVQGLIDREEGNHIEALRHLQKSAELNPRNIETYKEIGRTL---------YIMGRFSQA 120
               .:|.:...|...:|....||..|.::.:|.........||.|.:         |.|||.|:|
Mouse    80 EKATMYDLLAYIKHLDGESKAALECLGQAEDLRKSEHNDQSEIRRLVTWGNYAWIYYHMGRLSEA 144

  Fly   121 LGVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQKDVASQQQDEARTYFELAVQ---------S 176
            .....:..|...:..:.......||......|:    :...:.:.|:..||.|::         |
Mouse   145 QAYVDKVRQVCQKFANPYSMECPELECEEGWTR----LKCGRNERAKMCFEKALEEKPKDPECSS 205

  Fly   177 GRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPENS--EVLIEISVLYLKINETQKAHDRLAE 239
            |..:..: ||.|  :.:||:  :::.|:..:.|.|:|.  :||:.:.:|            |:.|
Mouse   206 GMAIAMF-RLEE--KPEKQF--SVDALKQAMELNPQNQYLKVLLALKLL------------RMGE 253

  Fly   240 VVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNNIGLCFFKKQ-KFIVAI 303
            ....||       |...|:.::.|..| .|.|.:|                  |:||: ....||
Mouse   254 EAEGER-------LIKDALGKAPNQTD-VLQKAAQ------------------FYKKKGNLDRAI 292

  Fly   304 SSLRKSVWLSPLNYNALYNL 323
            ..|.|:: .|.:|.:.||:|
Mouse   293 ELLGKAL-RSTVNNSPLYSL 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BBS4NP_610636.1 TPR repeat 68..95 CDD:276809 6/26 (23%)
LapB 70..347 CDD:442196 61/275 (22%)
TPR repeat 100..130 CDD:276809 9/38 (24%)
TPR repeat 136..175 CDD:276809 7/38 (18%)
TPR repeat 179..209 CDD:276809 6/29 (21%)
TPR repeat 214..242 CDD:276809 5/29 (17%)
TPR repeat 249..277 CDD:276809 7/27 (26%)
BepA 281..423 CDD:443813 12/44 (27%)
TPR repeat 283..311 CDD:276809 7/28 (25%)
TPR repeat 316..346 CDD:276809 4/8 (50%)
TPR repeat 351..377 CDD:276809
Ifit3XP_011245453.1 TPR_12 82..157 CDD:315987 17/74 (23%)
TPR repeat 82..110 CDD:276809 6/27 (22%)
TPR repeat 115..154 CDD:276809 9/38 (24%)
TPR 127..368 CDD:440225 51/233 (22%)
TPR repeat 167..195 CDD:276809 7/31 (23%)
TPR repeat 200..233 CDD:276809 8/37 (22%)
TPR repeat 272..300 CDD:276809 11/47 (23%)
Blue background indicates that the domain is not in the aligned region.

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