Protein Alignment Spn47C and SERPINB11

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_536723.2
• Gene: SERPINB11 / 89778
• HGNCID: 14221
• Length: 392
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 110/400 - (27%)
• Similarity: 199/400 - (49%)
• Gaps: 37/400 - (9%)

  Fly    10 SLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSE 74
            |||.:.:.|..::|:.||......|:..|......|:::|.:||.|::.::|..  :|..|:..:
Human     3 SLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEK--VLHFSHTVD 65

  Fly    75 VAKQHAESWTDECSCAKKG-------------------VALRLVTRLYVNEEEKIRTDFNDMALE 120
            ..|   ..:.|...|::.|                   ..|.:..|||..:.......:...:.:
Human    66 SLK---PGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEK 127

  Fly   121 FFNAEAYSLNY-LNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIF 184
            ::.|...:::: .:.|::.|.:|.|:|..|...|.|||.....:..|.::|||:::|:.:|...|
Human   128 WYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKF 192

  Fly   185 PQQLTQIDDFWINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLP 249
            ..:.|....|.::..:.:.|.||.|||.|:....|:.:.|:|:||:..:.|:|:|:||..|..|.
Human   193 QVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLK 257

  Fly   250 ELEEKLGQLDMNEVAAKSLM--KEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFE 312
            ::|::|.....:|..:.|.|  :||:|.:|:|::|...:|...|:.:|:..:|:..:||||.:
Human   258 QIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGM-- 320

  Fly   313 MKTPQK---ISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIR--DRKN 372
              :|.|   :|:|.||.:|:|:|.|.|.| .|......:|..|.|..|||:.||:|.||  ....
Human   321 --SPTKGLYLSKAIHKSYLDVSEEGTEAA-AATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNT 382

  Fly   373 VYFVGHFVKP 382
            :.|.|....|
Human   383 ILFCGKLASP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	106/395 (27%)
SERPINB11	NP_536723.2	serpinB11_epipin	1..392	CDD:381036	109/398 (27%)
		RCL. /evidence=ECO:0000250	341..365		8/24 (33%)