Protein Alignment Spn47C and SERPING1

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_000053.2
• Gene: SERPING1 / 710
• HGNCID: 1228
• Length: 500
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 52/269 - (19%)
• Similarity: 95/269 - (35%)
• Gaps: 84/269 - (31%)

  Fly    66 TTQDDFEGNAE---------------LLGDNEDSTGSFHALCMVAQGAGFEK----IEDLLSLD- 110
            |..|||.|.::               :...:.:..||:..:....:....||    :.|.|:..
Human    12 TDLDDFIGPSQSCIKPVTVAKKPGSGIAKIHIEDDGSYFQVNPDGRSQKLEKAKVSLNDCLACSG 76

  Fly   111 --TTVLKIIYTSQT--EQYQLNASNLVRFDHLRELHVQSLQAQLLRFSLDAELPVARLHLESLEL 171
              |:...|:.|.|:  |..::..:|.|.....:.|.|.|:..| .|.||     .||..|:|.:.
Human    77 CVTSAETILITQQSHEELRKVLDANKVAAPGQQRLVVVSVSPQ-SRASL-----AARFQLDSTDT 135

  Fly   172 VRTEPPTVLDRTQPSLTG----LGLQSSPDTT-AYQIVATDEEEEIVV---DGSNGADSL----- 223
            .|            .||.    :|:....||. |......:.::|.|.   :.:|..::|
Human   136 AR------------KLTSFFKKIGVHFVFDTAFARNFSLLESQKEFVQRFREQANSREALPMLAS 188

  Fly   224 ---------TETFELEIVPY----------------EVYKRELASTSNVSFYGWSNLTALSIHDC 263
                     .:|....|:||                :.:.::...|.:..::    :|.:..:|.
Human   189 ACPGWICYAEKTHGNFILPYISTARSPQQVMGSLIKDFFAQQQLLTPDKIYH----VTVMPCYDK 249

  Fly   264 QLESLHPDF 272
            :||:..|||
Human   250 KLEASRPDF 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	52/269 (19%)
SERPING1	NP_000053.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..43		0/22 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..118		12/52 (23%)
		7 X 4 AA tandem repeats of [QE]-P-T-[TQ]	85..119		8/33 (24%)
		serpinG1_C1-INH	136..496	CDD:381006	23/139 (17%)